Literature DB >> 1844960

Clonal variation within a mucosal isolate derived from a patient with Leishmania (Viannia) braziliensis infection.

C A Cuba-Cuba1, D Evans, A de C Rosa, P D Marsden.   

Abstract

Three isolates over 5 years from a patient with persistent relapsing mucosal leishmaniasis due to Leishmania (Viannia) braziliensis and 7 clones from one of these isolates were studied by zymodemes and serodemes analysis. Results showed evidences of clonal phenotypic variation. Eight isoenzymes markers demonstrated clear differences on Cellulose Acetate (CA) and thin starch gel electrophoresis. Also a panel of specific monoclonal antibodies showed such differences. Our observations provide additional evidence that Leishmania (Viannia) braziliensis is composed by subpopulations of parasites with peculiar biochemical and antigenic characteristics.

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Year:  1991        PMID： 1844960     DOI： 10.1590/s0036-46651991000500002

Source DB:  PubMed          Journal:  Rev Inst Med Trop Sao Paulo        ISSN： 0036-4665            Impact factor:   1.846


  3 in total

1.  Intra-strain clonal phenotypic variation of Tritrichomonas foetus is related to the cytotoxicity exerted by the parasite to cultured cells.

Authors:  Bruno da Rocha-Azevedo; Mariane B de Melo-Braga; Fernando C e Silva-Filho
Journal:  Parasitol Res       Date:  2004-12-10       Impact factor: 2.289

2.  Virulence of Leishmania infantum is expressed as a clonal and dominant phenotype in experimental infections.

Authors:  Y J Garin; A Sulahian; F Pratlong; P Meneceur; J P Gangneux; E Prina; J P Dedet; F Derouin
Journal:  Infect Immun       Date:  2001-12       Impact factor: 3.441

3.  Cutaneous leishmaniasis in the Peruvian Andes: an epidemiological study of infection and immunity.

Authors:  C R Davies; E A Llanos-Cuentas; S D Pyke; C Dye
Journal:  Epidemiol Infect       Date:  1995-04       Impact factor: 2.451
  3 in total

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