I Bilgic1, N Ozalp, M Tez, M Koc. 1. Fifth Department of Surgery, Ankara Numune Education and Research Hospital, Ankara, Turkey.
Abstract
BACKGROUND: Angiogenetic factors play an important role in the formation of new blood vessels involved in the growth and metastatic spread of solid tumors, but there is limited information regarding the clinical significance of serum bFGF levels in gastric cancer patients. PATIENTS AND METHODS: Serum bFGF concentrations were measured by quantitative sandwich enzyme immunoassay technique in 30 controls and in 30 gastric cancer patients before surgery. The association between preoperative serum bFGF levels and clinical pathological features were evaluated. RESULTS: Preoperative serum bFGF levels in patients with gastric cancer were significantly higher than those in control patients (p=0.027). On the other hand; there is no relationship between serum bFGF levels and clinical-pathologic parameters in gastric cancer patients. CONCLUSION: Circulating bFGF might not be a marker suitable for assessing tumor progression (Tab. 1, Ref. 7). Full Text (Free, PDF) www.bmj.sk.
BACKGROUND: Angiogenetic factors play an important role in the formation of new blood vessels involved in the growth and metastatic spread of solid tumors, but there is limited information regarding the clinical significance of serum bFGF levels in gastric cancerpatients. PATIENTS AND METHODS: Serum bFGF concentrations were measured by quantitative sandwich enzyme immunoassay technique in 30 controls and in 30 gastric cancerpatients before surgery. The association between preoperative serum bFGF levels and clinical pathological features were evaluated. RESULTS: Preoperative serum bFGF levels in patients with gastric cancer were significantly higher than those in control patients (p=0.027). On the other hand; there is no relationship between serum bFGF levels and clinical-pathologic parameters in gastric cancerpatients. CONCLUSION: Circulating bFGF might not be a marker suitable for assessing tumor progression (Tab. 1, Ref. 7). Full Text (Free, PDF) www.bmj.sk.
Authors: Jan Rykala; Karolina Przybylowska; Ireneusz Majsterek; Grazyna Pasz-Walczak; Andrzej Sygut; Adam Dziki; Piotr Kuna Journal: Arch Med Sci Date: 2014-01-23 Impact factor: 3.318
Authors: Andrzej Eljaszewicz; Małgorzata Wiese; Anna Helmin-Basa; Michal Jankowski; Lidia Gackowska; Izabela Kubiszewska; Wojciech Kaszewski; Jacek Michalkiewicz; Wojciech Zegarski Journal: Mediators Inflamm Date: 2013-03-17 Impact factor: 4.711