Literature DB >> 18446819

Is therapy with calcium and vitamin D and parathyroid autotransplantation useful in total thyroidectomy for preventing hypocalcemia?

Bassam Abboud1, Ghassan Sleilaty, Salam Zeineddine, Carla Braidy, Rony Aouad, Cyril Tohme, Roger Noun, Riad Sarkis.   

Abstract

BACKGROUND: Routine calcium and vitamin D administration and routine autotransplantation of parathyroid glands can prevent hypocalcemia after total thyroidectomy.
METHODS: Routine autotransplantation of 1 or more parathyroid glands and oral calcium and vitamin D supplementation was used in 252 patients.
RESULTS: One, 2, or 3 parathyroid glands were autotransplanted in 223, 27, and 2 patients, respectively. Routine oral calcium and vitamin D was administered in postoperative period in all patients. Postoperative hypocalcemia occurred in 17%, of whom 1.6% had minor symptoms related to hypocalcemia. No patient developed permanent hypocalcemia during the follow-up period. The postoperative stay was 1 day in 93.6% of the cases. The incidence of postoperative hypocalcemia and hospital stay was higher in patients who underwent autotransplantation of more than 1 parathyroid gland.
CONCLUSIONS: Routine oral calcium and vitamin D supplementation and autotransplantation of at least 1 parathyroid gland effectively reduced symptomatic hypocalcemia and permanent hypoparathyroidism in total thyroidectomy.

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Year:  2008        PMID: 18446819     DOI: 10.1002/hed.20836

Source DB:  PubMed          Journal:  Head Neck        ISSN: 1043-3074            Impact factor:   3.147


  13 in total

1.  Failure of fragmented parathyroid gland autotransplantation to prevent permanent hypoparathyroidism after total thyroidectomy.

Authors:  Leyre Lorente-Poch; Juan Sancho; Jose Luis Muñoz; Lander Gallego-Otaegui; Carlos Martínez-Ruiz; Antonio Sitges-Serra
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4.  Outcome of parathyroid function after total thyroidectomy when calcium supplementation is administered routinely versus exclusively to symptomatic patients: A prospective randomized clinical trial.

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Authors:  S R Priya; Chandrashekhar Dravid
Journal:  Indian J Surg Oncol       Date:  2019-11-26

6.  Role of postoperative vitamin D and/or calcium routine supplementation in preventing hypocalcemia after thyroidectomy: a systematic review and meta-analysis.

Authors:  Amal Alhefdhi; Haggi Mazeh; Herbert Chen
Journal:  Oncologist       Date:  2013-05-01

7.  Graves' ophthalmopathy as an indication increased the risk of hypoparathyroidism after bilateral thyroidectomy.

Authors:  Kai-Pun Wong; Brian Hung-Hin Lang
Journal:  World J Surg       Date:  2011-10       Impact factor: 3.352

8.  Evaluation of surgical risk and prognosis between thyroid nodules of size <1 and ≥1 cm.

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Journal:  Gland Surg       Date:  2019-12

9.  Total thyroidectomy as primary surgical management for thyroid disease: surgical therapy experience from 5559 thyroidectomies in a less-developed region.

Authors:  Jisheng Hu; Nan Zhao; Rui Kong; Dawei Wang; Bei Sun; Lifeng Wu
Journal:  World J Surg Oncol       Date:  2016-01-22       Impact factor: 2.754

10.  Evaluation of a TPTX model induced by ischemia.

Authors:  Haoran Yuan; Yongzhao Shi; Yinghua Li; Lin Yang; Yan Tang; Zhiqing Hu; Ran Du; Xueqing Li; Lingbin Gu; Hui Wang; Chenhui Xi; Chenghui Tang
Journal:  Exp Anim       Date:  2017-07-03
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