Literature DB >> 18444328

How cells clean house.

Vojo Deretic1, Daniel J Klionsky.   

Abstract

Inside the cytoplasm of a living cell, organelles called autophagosomes continually engulf bits of cytoplasm, along with damaged cell parts and invading bacteria and viruses. The "sweepings" are carried to digestive organelles for breakup and recycling. The process is called autophagy. Cell biologists are learning about autophagy in great detail by tracing the protein signals that drive and control the process. A fuller understanding of autophagy is opening up new options for treating cancer, infectious disease, immune disorders and dementia, and it may one day even help to slow down aging.

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Year:  2008        PMID： 18444328     DOI： 10.1038/scientificamerican0508-74

Source DB:  PubMed          Journal:  Sci Am        ISSN： 0036-8733            Impact factor:   2.142


  9 in total

1.  Autophagy protein Rubicon mediates phagocytic NADPH oxidase activation in response to microbial infection or TLR stimulation.

Authors:  Chul-Su Yang; Jong-Soo Lee; Mary Rodgers; Chan-Ki Min; June-Yong Lee; Hee Jin Kim; Kwang-Hoon Lee; Chul-Joong Kim; Byungha Oh; Ebrahim Zandi; Zhenyu Yue; Igor Kramnik; Chengyu Liang; Jae U Jung
Journal:  Cell Host Microbe       Date:  2012-03-15       Impact factor: 21.023

2.  Propeptide of aminopeptidase 1 protein mediates aggregation and vesicle formation in cytoplasm-to-vacuole targeting pathway.

Authors:  Mariana Morales Quinones; Jared T Winston; Per E Stromhaug
Journal:  J Biol Chem       Date:  2011-11-28       Impact factor: 5.157

Review 3.  The intricacy of nuclear membrane dynamics during nucleophagy.

Authors:  Dalibor Mijaljica; Mark Prescott; Rodney J Devenish
Journal:  Nucleus       Date:  2010-02-16       Impact factor: 4.197

Review 4.  Links between autophagy, innate immunity, inflammation and Crohn's disease.

Authors:  Vojo Deretic
Journal:  Dig Dis       Date:  2009-09-24       Impact factor: 2.404

Review 5.  Autophagy and pattern recognition receptors in innate immunity.

Authors:  Monica Delgado; Sudha Singh; Sergio De Haro; Sharon Master; Marisa Ponpuak; Christina Dinkins; Wojciech Ornatowski; Isabelle Vergne; Vojo Deretic
Journal:  Immunol Rev       Date:  2009-01       Impact factor: 12.988

6.  Heterogeneity in a large pedigree with Danon disease: Implications for pathogenesis and management.

Authors:  Jonathan C P Roos; Matthew J Daniels; Elizabeth Morris; Hanna I Hyry; Timothy M Cox
Journal:  Mol Genet Metab       Date:  2017-06-21       Impact factor: 4.797

Review 7.  The intriguing life of autophagosomes.

Authors:  Dalibor Mijaljica; Mark Prescott; Rodney J Devenish
Journal:  Int J Mol Sci       Date:  2012-03-19       Impact factor: 6.208

Review 8.  Hypertrophic Cardiomyopathy in Children: Pathophysiology, Diagnosis, and Treatment of Non-sarcomeric Causes.

Authors:  Emanuele Monda; Marta Rubino; Michele Lioncino; Francesco Di Fraia; Roberta Pacileo; Federica Verrillo; Annapaola Cirillo; Martina Caiazza; Adelaide Fusco; Augusto Esposito; Fabio Fimiani; Giuseppe Palmiero; Giuseppe Pacileo; Paolo Calabrò; Maria Giovanna Russo; Giuseppe Limongelli
Journal:  Front Pediatr       Date:  2021-02-25       Impact factor: 3.569

9.  Autophagy and exosomes in the aged retinal pigment epithelium: possible relevance to drusen formation and age-related macular degeneration.

Authors:  Ai Ling Wang; Thomas J Lukas; Ming Yuan; Nga Du; Mark O Tso; Arthur H Neufeld
Journal:  PLoS One       Date:  2009-01-08       Impact factor: 3.240
  9 in total

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