Literature DB >> 18443599

Effect of weight-bearing activities on bone mineral density in spinal cord injured patients during the period of the first two years.

V Alekna1, M Tamulaitiene, T Sinevicius, A Juocevicius.   

Abstract

STUDY
DESIGN: Prospective study on patients with spinal cord injuries.
OBJECTIVES: To evaluate the loss of bone mineral density (BMD) in various body regions of patients with spinal cord injury (SCI) and its dependence on weight bearing activities during 2 years post injury.
METHODS: BMD of the whole body was measured in patients with SCI. Baseline measurement was performed in 6-16 weeks after SCI, the second and the third-respectively 12 and 24 months after injury. Fifty-four subjects were selected and divided into two groups: standing and non-standing. From these groups 27 pairs were made according to gender, age and height.
RESULTS: There was found to be a well-marked decrease in BMD values for lower extremities, but there was no significant difference between paraplegic and tetraplegic patients 1 and 2 year after injury. Leg BMD reduced by 19.62% (95% CI, 17-22%) in the standing group and by 24% (95% CI, 21-27%) in non-standing group during the first year. Two years after SCI patients in standing group had significantly higher leg BMD-1.018 g/cm(2) (95% CI, 0.971-1.055 g/cm(2)) than in the non-standing group-0.91 g/cm(2) (95% CI, 0.872-0.958 g/cm(2)) (P<or=0.0001).
CONCLUSION: SCI patients who performed daily standing >or=1 h and not less than 5 days per week, had significantly higher BMD in the lower extremities after 2 years in comparison to those patients who did not perform standing.

Entities:  

Mesh:

Year:  2008        PMID: 18443599     DOI: 10.1038/sc.2008.36

Source DB:  PubMed          Journal:  Spinal Cord        ISSN: 1362-4393            Impact factor:   2.772


  22 in total

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2.  Hyperventilation during orthostatic challenge in spinal cord-injured humans.

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Review 3.  Rehabilitation Interventions to modify endocrine-metabolic disease risk in Individuals with chronic Spinal cord injury living in the Community (RIISC): A systematic review and scoping perspective.

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4.  Precision of dual-energy X-ray absorptiometry of the knee and heel: methodology and implications for research to reduce bone mineral loss after spinal cord injury.

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Review 6.  Mechanical factors and bone health: effects of weightlessness and neurologic injury.

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7.  Factors influencing bone loss in paraplegia.

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8.  The impact of supported standing on well-being and quality of life.

Authors:  Birgitta Nordström; Annika Näslund; Margareta Eriksson; Lars Nyberg; Lilly Ekenberg
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9.  Whole-body vibration can attenuate the deterioration of bone mass and trabecular bone microstructure in rats with spinal cord injury.

Authors:  A Minematsu; Y Nishii; H Imagita; D Takeshita; S Sakata
Journal:  Spinal Cord       Date:  2015-12-22       Impact factor: 2.772

10.  Effect of chronic activity-based therapy on bone mineral density and bone turnover in persons with spinal cord injury.

Authors:  Todd Anthony Astorino; Eric T Harness; Kara A Witzke
Journal:  Eur J Appl Physiol       Date:  2013-10-06       Impact factor: 3.078

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