Literature DB >> 18439927

[Precoce survey: a new self-assessment patient card for early detection and management of Parkinson disease fluctuations].

J-P Azulay1, F Durif, R Rogez, C Tranchant, I Bourdeix, K Rerat.   

Abstract

It has been known for more than 30 years that the efficiency of the dopaminergic treatments can wear off. Currently, motor fluctuations and especially non-motor fluctuations (dysautonomic, cognitive/psychiatric or sensory/pain) remain often underdiagnosed in the first years of treatment. The patient self-questionnaire used in this study has been developed and validated in the United States. Its French version has been tested in daily practice in a study with 938 Parkinson's patients followed-up by movement disorders specialists. Use of this self-assessment patient card has resulted in the detection of fluctuations in 49% of patients, considered nonfluctuating by neurologists after a clinical assessment. The impact of these fluctuations unknown at first is significant, since these motor and/or non motor symptoms are considered troublesome or perturbing for daily life activities by 70% of fluctuating patients. The investigators have recognized the usefulness of this self-assessment in order to detect fluctuations in 81% of fluctuating patients, which lead them to modify the treatment in 76% of them.

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Year:  2008        PMID: 18439927     DOI: 10.1016/j.neurol.2008.01.003

Source DB:  PubMed          Journal:  Rev Neurol (Paris)        ISSN: 0035-3787            Impact factor:   2.607


  3 in total

1.  Linguistic, psychometric validation and diagnostic ability assessment of an Italian version of a 19-item wearing-off questionnaire for wearing-off detection in Parkinson's disease.

Authors:  Giovanni Abbruzzese; Angelo Antonini; Paolo Barone; Fabrizio Stocchi; Tiziano Tamburini; Laura Bernardi; Marianna Amboni; Laura Vacca; Valeria Posocco; Delia Colombo
Journal:  Neurol Sci       Date:  2012-02-04       Impact factor: 3.307

Review 2.  Clinimetrics of the 9- and 19-Item Wearing-Off Questionnaire: A Systematic Review.

Authors:  Carlos E Mantese; Artur Schumacher-Schuh; Carlos R M Rieder
Journal:  Parkinsons Dis       Date:  2018-04-01

3.  Evaluation of the Isoflavone Genistein as Reversible Human Monoamine Oxidase-A and -B Inhibitor.

Authors:  Najla O Zarmouh; Samia S Messeha; Faisel M Elshami; Karam F A Soliman
Journal:  Evid Based Complement Alternat Med       Date:  2016-03-28       Impact factor: 2.629

  3 in total

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