Literature DB >> 18438792

Diagnostic and treatment delays in recurrent Clostridium difficile-associated disease.

Danielle Scheurer1.   

Abstract

BACKGROUND: Because Clostridium difficile-associated disease (CDAD) is primarily an inpatient issue, hospitalists are at the forefront of the timely diagnosis and treatment of patients with this disease.
DESIGN: The study was a retrospective cohort of all inpatients with CDAD at Brigham and Women's Hospital from 1997 to 2004 in order to determine the time to diagnosis and treatment in initial and recurrent episodes of disease.
RESULTS: The mean time to sampling, between 2.09 and 2.24 days, was not significantly different between initial and recurrent CDAD hospital episodes. The mean time to treatment (from symptoms and sampling) was shorter in recurrent episodes but was still 2.5 days.
CONCLUSIONS: Patients with recurrent disease were more likely to be treated earlier but not diagnosed earlier than those with initial disease. Because both groups had significant diagnostic and treatment delays, this is an area in which hospitalists can have a major impact on patient care. (c) 2008 Society of Hospital Medicine.

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Year:  2008        PMID: 18438792     DOI: 10.1002/jhm.277

Source DB:  PubMed          Journal:  J Hosp Med        ISSN: 1553-5592            Impact factor:   2.960


  10 in total

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2.  Clostridium difficile in the Long-Term Care Facility: Prevention and Management.

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3.  Evaluation of the Use of Rectal Swabs for Laboratory Diagnosis of Clostridium difficile Infection.

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Review 4.  Clostridium difficile associated infection, diarrhea and colitis.

Authors:  Perry Hookman; Jamie S Barkin
Journal:  World J Gastroenterol       Date:  2009-04-07       Impact factor: 5.742

5.  Rapid, accurate, and on-site detection of C. difficile in stool samples.

Authors:  Marije K Bomers; Frederik P Menke; Richard S Savage; Christina M J E Vandenbroucke-Grauls; Michiel A van Agtmael; James A Covington; Yvo M Smulders
Journal:  Am J Gastroenterol       Date:  2015-03-31       Impact factor: 10.864

6.  Equivalent Performance of the Cobas® Cdiff Test for Use on the Cobas® Liat® System and the Cobas® 4800 System.

Authors:  Sachin K Garg; Kyle Lu; John Duncan; Lance R Peterson; Oliver Liesenfeld
Journal:  Eur J Microbiol Immunol (Bp)       Date:  2017-12-05

7.  Using Dog Scent Detection as a Point-of-Care Tool to Identify Toxigenic Clostridium difficile in Stool.

Authors:  Maureen T Taylor; Janine McCready; George Broukhanski; Sakshi Kirpalaney; Haydon Lutz; Jeff Powis
Journal:  Open Forum Infect Dis       Date:  2018-08-22       Impact factor: 3.835

8.  Using a dog's superior olfactory sensitivity to identify Clostridium difficile in stools and patients: proof of principle study.

Authors:  Marije K Bomers; Michiel A van Agtmael; Hotsche Luik; Merk C van Veen; Christina M J E Vandenbroucke-Grauls; Yvo M Smulders
Journal:  BMJ       Date:  2012-12-13

9.  A simulation-based assessment of strategies to control Clostridium difficile transmission and infection.

Authors:  Michael A Rubin; Makoto Jones; Molly Leecaster; Karim Khader; Willy Ray; Angela Huttner; Benedikt Huttner; Damon Toth; Theodore Sablay; Robert J Borotkanics; Dale N Gerding; Matthew H Samore
Journal:  PLoS One       Date:  2013-11-21       Impact factor: 3.240

10.  An Economic Analysis of Strategies to Control Clostridium Difficile Transmission and Infection Using an Agent-Based Simulation Model.

Authors:  Richard E Nelson; Makoto Jones; Molly Leecaster; Matthew H Samore; William Ray; Angela Huttner; Benedikt Huttner; Karim Khader; Vanessa W Stevens; Dale Gerding; Marin L Schweizer; Michael A Rubin
Journal:  PLoS One       Date:  2016-03-31       Impact factor: 3.240

  10 in total

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