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Literature DB >> 18438419

The exonuclease ERI-1 has a conserved dual role in 5.8S rRNA processing and RNAi.

Abstract

The exonuclease ERI-1 negatively regulates RNA interference in Caenorhabditis elegans and Schizosaccharomyces pombe, and is required for production of some C. elegans endogenous small interfering RNAs. We show that ERI-1 performs 3' end processing of the 5.8S ribosomal RNA in both C. elegans and S. pombe. In C. elegans, two protein isoforms of ERI-1 are localized to the cytoplasm, and each has distinct functions in ribosomal RNA processing and negative regulation of RNA interference.

Entities: Gene Species

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Year: 2008 PMID： 18438419 PMCID： PMC2910399 DOI： 10.1038/nsmb.1411

Source DB: PubMed Journal: Nat Struct Mol Biol ISSN： 1545-9985 Impact factor: 15.369

13 in total

1. Functional proteomics reveals the biochemical niche of C. elegans DCR-1 in multiple small-RNA-mediated pathways.

Authors: Thomas F Duchaine; James A Wohlschlegel; Scott Kennedy; Yanxia Bei; Darryl Conte; Kaming Pang; Daniel R Brownell; Sandra Harding; Shohei Mitani; Gary Ruvkun; John R Yates; Craig C Mello
Journal: Cell Date: 2006-01-27 Impact factor: 41.582

2. DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs.

Authors: Toru Fukuda; Kaoru Yamagata; Sally Fujiyama; Takahiro Matsumoto; Iori Koshida; Kimihiro Yoshimura; Masatomo Mihara; Masanori Naitou; Hideki Endoh; Takashi Nakamura; Chihiro Akimoto; Yoko Yamamoto; Takenobu Katagiri; Charles Foulds; Shinichiro Takezawa; Hirochika Kitagawa; Ken-ichi Takeyama; Bert W O'Malley; Shigeaki Kato
Journal: Nat Cell Biol Date: 2007-04-15 Impact factor: 28.824

Review 3. Processing of pre-ribosomal RNA in Saccharomyces cerevisiae.

Authors: J Venema; D Tollervey
Journal: Yeast Date: 1995-12 Impact factor: 3.239

4. SAF-Box, a conserved protein domain that specifically recognizes scaffold attachment region DNA.

Authors: M Kipp; F Göhring; T Ostendorp; C M van Drunen; R van Driel; M Przybylski; F O Fackelmayer
Journal: Mol Cell Biol Date: 2000-10 Impact factor: 4.272

5. Structure of the 80S ribosome from Saccharomyces cerevisiae--tRNA-ribosome and subunit-subunit interactions.

Authors: C M Spahn; R Beckmann; N Eswar; P A Penczek; A Sali; G Blobel; J Frank
Journal: Cell Date: 2001-11-02 Impact factor: 41.582

6. Coordinated nuclear export of 60S ribosomal subunits and NMD3 in vertebrates.

Authors: Christopher R Trotta; Elsebet Lund; Lawrence Kahan; Arlen W Johnson; James E Dahlberg
Journal: EMBO J Date: 2003-06-02 Impact factor: 11.598

7. Interacting endogenous and exogenous RNAi pathways in Caenorhabditis elegans.

Authors: Rosalind C Lee; Christopher M Hammell; Victor Ambros
Journal: RNA Date: 2006-02-17 Impact factor: 4.942

8. Ngl2p is a Ccr4p-like RNA nuclease essential for the final step in 3'-end processing of 5.8S rRNA in Saccharomyces cerevisiae.

Authors: Alex W Faber; Marie Van Dijk; Hendrik A Raué; Jan C Vos
Journal: RNA Date: 2002-09 Impact factor: 4.942

9. A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans.

Authors: Scott Kennedy; Duo Wang; Gary Ruvkun
Journal: Nature Date: 2004-02-12 Impact factor: 49.962

10. A 3' exonuclease that specifically interacts with the 3' end of histone mRNA.

Authors: Zbigniew Dominski; Xiao-cui Yang; Handan Kaygun; Michal Dadlez; William F Marzluff
Journal: Mol Cell Date: 2003-08 Impact factor: 17.970

30 in total

1. Distinct phases of siRNA synthesis in an endogenous RNAi pathway in C. elegans soma.

Authors: Jonathan I Gent; Ayelet T Lamm; Derek M Pavelec; Jay M Maniar; Poornima Parameswaran; Li Tao; Scott Kennedy; Andrew Z Fire
Journal: Mol Cell Date: 2010-01-28 Impact factor: 17.970

Review 2. New perspectives on the diversification of the RNA interference system: insights from comparative genomics and small RNA sequencing.

Authors: Alexander Maxwell Burroughs; Yoshinari Ando; L Aravind
Journal: Wiley Interdiscip Rev RNA Date: 2013-12-05 Impact factor: 9.957

The exonuclease ERI-1 has a conserved dual role in 5.8S rRNA processing and RNAi.

1. Functional proteomics reveals the biochemical niche of C. elegans DCR-1 in multiple small-RNA-mediated pathways.

2. DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs.

Review 3. Processing of pre-ribosomal RNA in Saccharomyces cerevisiae.

4. SAF-Box, a conserved protein domain that specifically recognizes scaffold attachment region DNA.

5. Structure of the 80S ribosome from Saccharomyces cerevisiae--tRNA-ribosome and subunit-subunit interactions.

6. Coordinated nuclear export of 60S ribosomal subunits and NMD3 in vertebrates.

7. Interacting endogenous and exogenous RNAi pathways in Caenorhabditis elegans.

8. Ngl2p is a Ccr4p-like RNA nuclease essential for the final step in 3'-end processing of 5.8S rRNA in Saccharomyces cerevisiae.

9. A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans.

10. A 3' exonuclease that specifically interacts with the 3' end of histone mRNA.

1. Distinct phases of siRNA synthesis in an endogenous RNAi pathway in C. elegans soma.

Review 2. New perspectives on the diversification of the RNA interference system: insights from comparative genomics and small RNA sequencing.

3. Abundant and dynamically expressed miRNAs, piRNAs, and other small RNAs in the vertebrate Xenopus tropicalis.

4. Sequence and generation of mature ribosomal RNA transcripts in Dictyostelium discoideum.

5. The RNA phosphatase PIR-1 regulates endogenous small RNA pathways in C. elegans.

6. Eri1 degrades the stem-loop of oligouridylated histone mRNAs to induce replication-dependent decay.

7. Structure of histone mRNA stem-loop, human stem-loop binding protein, and 3'hExo ternary complex.

8. The final step in 5.8S rRNA processing is cytoplasmic in Saccharomyces cerevisiae.

9. rRNA maturation in yeast cells depleted of large ribosomal subunit proteins.

10. deepBase: a database for deeply annotating and mining deep sequencing data.