OBJECTIVE: To study the association between smoking, smoking cessation and aortic arc calcification (AAC) in an older Chinese population. METHODS: A total of 3022 men and 7279 women aged 50-85 years were recruited and received a medical check-up including measurement of fasting plasma vascular risk factors. Two radiologists reviewed the posterior-anterior plain chest X-ray radiographs and assessed AAC together. Information on smoking status, socioeconomic and lifestyle factors was collected. RESULTS: The crude prevalence of AAC in men (38.58%) was lower than that in women (41.37%). The adjusted odds ratios of AAC increased significantly across never, ex- and current smokers in both genders. Dose-response relationships were observed among current smokers for smoking amount (cigarettes/day), smoking duration (years) and cigarette pack-years in both genders (all p<0.01). The odds ratios decreased significantly (p=0.018) with longer duration of quitting in light ex-smoking men (<23.5 pack-years) but showed no beneficial effect (p=0.72) for heavy ex-smokers (>or=23.5 pack-years). CONCLUSION: Smoking increased the risk of AAC in Chinese, while smoking cessation decreased the risk only in male light ex-smokers. Chest X-ray is a cheap and simple method to detect AAC, which should be an important warning signal for immediate smoking cessation.
OBJECTIVE: To study the association between smoking, smoking cessation and aortic arc calcification (AAC) in an older Chinese population. METHODS: A total of 3022 men and 7279 women aged 50-85 years were recruited and received a medical check-up including measurement of fasting plasma vascular risk factors. Two radiologists reviewed the posterior-anterior plain chest X-ray radiographs and assessed AAC together. Information on smoking status, socioeconomic and lifestyle factors was collected. RESULTS: The crude prevalence of AAC in men (38.58%) was lower than that in women (41.37%). The adjusted odds ratios of AAC increased significantly across never, ex- and current smokers in both genders. Dose-response relationships were observed among current smokers for smoking amount (cigarettes/day), smoking duration (years) and cigarette pack-years in both genders (all p<0.01). The odds ratios decreased significantly (p=0.018) with longer duration of quitting in light ex-smoking men (<23.5 pack-years) but showed no beneficial effect (p=0.72) for heavy ex-smokers (>or=23.5 pack-years). CONCLUSION: Smoking increased the risk of AAC in Chinese, while smoking cessation decreased the risk only in male light ex-smokers. Chest X-ray is a cheap and simple method to detect AAC, which should be an important warning signal for immediate smoking cessation.
Authors: Marco Canepa; Pietro Ameri; Majd AlGhatrif; Gabriele Pestelli; Yuri Milaneschi; James B Strait; Francesco Giallauria; Giorgio Ghigliotti; Claudio Brunelli; Edward G Lakatta; Luigi Ferrucci Journal: Atherosclerosis Date: 2014-05-08 Impact factor: 5.162
Authors: Chao Qiang Jiang; Bin Liu; Bernard M Y Cheung; Tai Hing Lam; Jie Ming Lin; Ya Li Jin; Xiao Jun Yue; Kwok Leung Ong; Sidney Tam; Ka Sing Wong; Brian Tomlinson; Karen S L Lam; G Neil Thomas Journal: Eur J Hum Genet Date: 2010-06-23 Impact factor: 4.246
Authors: Mi Jung Lee; Dong Ho Shin; Seung Jun Kim; Hyung Jung Oh; Dong Eun Yoo; Kwang Il Ko; Hyang Mo Koo; Chan Ho Kim; Fa Mee Doh; Jung Tak Park; Seung Hyeok Han; Tae-Hyun Yoo; Kyu Hun Choi; Shin-Wook Kang Journal: PLoS One Date: 2012-11-07 Impact factor: 3.240
Authors: Tao Wang; Chao Qiang Jiang; Lin Xu; Wei Sen Zhang; Feng Zhu; Ya Li Jin; G Neil Thomas; Kar Keung Cheng; Tai Hing Lam Journal: BMC Public Health Date: 2018-11-06 Impact factor: 3.295
Authors: Tai Hing Lam; Lin Xu; Chao Qiang Jiang; Wei Sen Zhang; Feng Zhu; Ya Li Jin; G Neil Thomas; Kar Keung Cheng Journal: PLoS One Date: 2018-04-26 Impact factor: 3.240