Literature DB >> 18436120

Quality of care of and outcomes for African Americans hospitalized with heart failure: findings from the OPTIMIZE-HF (Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients With Heart Failure) registry.

Clyde W Yancy1, William T Abraham, Nancy M Albert, Robert Clare, Wendy Gattis Stough, Mihai Gheorghiade, Barry H Greenberg, Christopher M O'Connor, Lilin She, Jie Lena Sun, James B Young, Gregg C Fonarow.   

Abstract

OBJECTIVES: We sought to examine the characteristics, quality of care, and clinical outcomes for a large cohort of African-American patients hospitalized with heart failure (HF) in centers participating in a quality improvement initiative.
BACKGROUND: Heart failure in African Americans is characterized by variations in natural history, lesser response to evidence-based therapies, and disparate health care. We hypothesized that a performance improvement program will achieve similar adherence to quality measures in African Americans admitted with HF compared with non-African Americans.
METHODS: The OPTIMIZE-HF (Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients With Heart Failure) registry-based performance-improvement program includes a pre-specified 10% subgroup with 60- to 90-day follow-up. Data on quality of care measures and outcomes were analyzed for 8,608 African-American patients compared with 38,501 non-African-American patients.
RESULTS: African Americans were significantly younger and more likely to receive evidence-based medications but less likely to receive discharge instructions and smoking cessation counseling. In multivariable analyses, African-American race was an independent predictor of lower in-hospital mortality (odds ratio 0.71; 95% confidence interval 0.57 to 0.87; p < 0.001) but similar hospital length of stay. After multivariable adjustment, post-discharge outcomes were similar for American-American and non-African-American patients, but African-American race was associated with higher angiotensin-converting enzyme inhibitor prescription and left ventricular function assessment; no other HF quality indicators were influenced by race.
CONCLUSIONS: In the context of a performance-improvement program, African Americans with HF received similar or better treatment with evidence-based medications, less discharge counseling, had better in-hospital survival, and similar adjusted risk of follow-up death/repeat hospital stay.

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Year:  2008        PMID: 18436120     DOI: 10.1016/j.jacc.2008.01.028

Source DB:  PubMed          Journal:  J Am Coll Cardiol        ISSN: 0735-1097            Impact factor:   24.094


  24 in total

1.  Isosorbide dinitrate and hydralazine as therapy for African Americans with heart failure; a failed paradigm?

Authors:  Clyde W Yancy; Arthur Feldman
Journal:  Clin Transl Sci       Date:  2009-08       Impact factor: 4.689

Review 2.  Global perspectives in hospitalized heart failure: regional and ethnic variation in patient characteristics, management, and outcomes.

Authors:  Andrew P Ambrosy; Mihai Gheorghiade; Ovidiu Chioncel; Robert J Mentz; Javed Butler
Journal:  Curr Heart Fail Rep       Date:  2014-12

3.  Race, exercise training, and outcomes in chronic heart failure: findings from Heart Failure - a Controlled Trial Investigating Outcomes in Exercise TraiNing (HF-ACTION).

Authors:  Robert J Mentz; Vera Bittner; Phillip J Schulte; Jerome L Fleg; Ileana L Piña; Steven J Keteyian; Gordon Moe; Anil Nigam; Ann M Swank; Anekwe E Onwuanyi; Meredith Fitz-Gerald; Andrew Kao; Stephen J Ellis; William E Kraus; David J Whellan; Christopher M O'Connor
Journal:  Am Heart J       Date:  2013-07-12       Impact factor: 4.749

Review 4.  The current state of ethnic and racial disparities in cardiovascular care: lessons from the past and opportunities for the future.

Authors:  Jennifer Lewey; Niteesh K Choudhry
Journal:  Curr Cardiol Rep       Date:  2014       Impact factor: 2.931

Review 5.  Transthyretin Cardiac Amyloidosis in Black Americans.

Authors:  Keyur B Shah; Anit K Mankad; Adam Castano; Olakunle O Akinboboye; Phillip B Duncan; Icilma V Fergus; Mathew S Maurer
Journal:  Circ Heart Fail       Date:  2016-06       Impact factor: 8.790

6.  Medication adherence is a mediator of the relationship between ethnicity and event-free survival in patients with heart failure.

Authors:  Jia-Rong Wu; Terry A Lennie; Marla J De Jong; Susan K Frazier; Seongkum Heo; Misook L Chung; Debra K Moser
Journal:  J Card Fail       Date:  2009-12-11       Impact factor: 5.712

7.  Smoking among women following heart transplantation: should we be concerned?

Authors:  Lorraine Evangelista; Alvina Ter-Galstanyan; Debra K Moser; Kathleen Dracup
Journal:  Prog Cardiovasc Nurs       Date:  2009-12

8.  Cholesterol treatment with statins: who is left out and who makes it to goal?

Authors:  Peter Franks; Daniel Tancredi; Paul Winters; Kevin Fiscella
Journal:  BMC Health Serv Res       Date:  2010-03-17       Impact factor: 2.655

9.  Heart failure with preserved ejection fraction in African Americans: The ARIC (Atherosclerosis Risk In Communities) study.

Authors:  Deepak K Gupta; Amil M Shah; Davide Castagno; Madoka Takeuchi; Laura R Loehr; Ervin R Fox; Kenneth R Butler; Thomas H Mosley; Dalane W Kitzman; Scott D Solomon
Journal:  JACC Heart Fail       Date:  2013-04       Impact factor: 12.035

10.  Changes in Left Ventricular Ejection Fraction Predict Survival and Hospitalization in Heart Failure With Reduced Ejection Fraction.

Authors:  Khadijah Breathett; Larry A Allen; James Udelson; Gordon Davis; Michael Bristow
Journal:  Circ Heart Fail       Date:  2016-10       Impact factor: 8.790

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