Literature DB >> 18434962

IL6 to the rescue.

Peter E Newburger1.   

Abstract

In addition to classic homeostatic granulocyte production mediated by G-CSF and GM-CSF, an independent pathway stimulated by IL6 complexed with its soluble receptor (sIL6R) contributes to emergency granulopoiesis.

Entities:  

Year:  2008        PMID： 18434962      PMCID： PMC2288711          DOI： 10.1182/blood-2008-01-133975

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


  3 in total

1.  Mice lacking both granulocyte colony-stimulating factor (CSF) and granulocyte-macrophage CSF have impaired reproductive capacity, perturbed neonatal granulopoiesis, lung disease, amyloidosis, and reduced long-term survival.

Authors:  J F Seymour; G J Lieschke; D Grail; C Quilici; G Hodgson; A R Dunn
Journal:  Blood       Date:  1997-10-15       Impact factor: 22.113

Review 2.  Interleukin-6 and its receptor: from bench to bedside.

Authors:  Jürgen Scheller; Stefan Rose-John
Journal:  Med Microbiol Immunol       Date:  2006-05-31       Impact factor: 3.402

3.  Notch ligand Delta-1 differentially modulates the effects of gp130 activation on interleukin-6 receptor alpha-positive and -negative human hematopoietic progenitors.

Authors:  Kentaro Yamamura; Kohshi Ohishi; Naoyuki Katayama; Keizo Kato; Tetsunori Shibasaki; Yuka Sugimoto; Eri Miyata; Hiroshi Shiku; Masahiro Masuya; Junji Nishioka; Tsutomu Nobori; Mitsuo Nishikawa; Yoshimasa Inagaki; Hidefumi Hiramatsu; Tatsutoshi Nakahata
Journal:  Cancer Sci       Date:  2007-07-23       Impact factor: 6.716
  3 in total
  2 in total

Review 1.  Hematopoietic cytokine-induced transcriptional regulation and Notch signaling as modulators of MDSC expansion.

Authors:  Sheinei J Saleem; Daniel H Conrad
Journal:  Int Immunopharmacol       Date:  2011-03-21       Impact factor: 4.932

2.  Alcohol impairs the myeloid proliferative response to bacteremia in mice by inhibiting the stem cell antigen-1/ERK pathway.

Authors:  John Nicholas Melvan; Robert W Siggins; William L Stanford; Connie Porretta; Steve Nelson; Gregory J Bagby; Ping Zhang
Journal:  J Immunol       Date:  2012-01-11       Impact factor: 5.422
  2 in total

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