Literature DB >> 18434575

Reduced amelogenin-MMP20 interactions in amelogenesis imperfecta.

K Tanimoto1, T Le, L Zhu, H E Witkowska, S Robinson, S Hall, P Hwang, P Denbesten, W Li.   

Abstract

Amelogenin with a proline 41 to threonine mutation (P41T) is hydrolyzed at a lower rate by matrix metalloproteinase 20 (MMP20), resulting in an inherited tooth enamel defect, amelogenesis imperfecta (AI). The aim of this study was to elucidate the effect of P41T on the interactions between amelogenin and MMP20, which may contribute to the formation of this type of AI. The interactions of a recombinant wild-type human amelogenin and its P41T mutant with recombinant human MMP20 were compared by substrate competition assay, pull-down assay, and surface plasmon resonance (SPR). The results showed that the binding of the P41T mutant amelogenin for MMP20 was significantly lower than that of wild-type amelogenin. Our study supports a model in which the P41T mutation reduces the interactions between amelogenin and MMP20, leading to decreased degradation of amelogenin by MMP20, and resulting in AI.

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Year:  2008        PMID： 18434575      PMCID： PMC3677966          DOI： 10.1177/154405910808700516

Source DB:  PubMed          Journal:  J Dent Res        ISSN： 0022-0345            Impact factor:   6.116


  30 in total

1.  Alternative splicing of the mouse amelogenin primary RNA transcript contributes to amelogenin heterogeneity.

Authors:  E C Lau; J P Simmer; P Bringas; D D Hsu; C C Hu; M Zeichner-David; F Thiemann; M L Snead; H C Slavkin; A G Fincham
Journal:  Biochem Biophys Res Commun       Date:  1992-11-16       Impact factor: 3.575

2.  Identification of the leucine-rich amelogenin peptide (LRAP) as the translation product of an alternatively spliced transcript.

Authors:  C W Gibson; E Golub; W D Ding; H Shimokawa; M Young; J Termine; J Rosenbloom
Journal:  Biochem Biophys Res Commun       Date:  1991-02-14       Impact factor: 3.575

3.  The role of proline in the proteolytic regulation of biologically active peptides.

Authors:  A Yaron
Journal:  Biopolymers       Date:  1987       Impact factor: 2.505

4.  Dental enamel matrix: sequences of two amelogenin polypeptides.

Authors:  A G Fincham; A B Belcourt; J D Termine; W T Butler; W C Cothran
Journal:  Biosci Rep       Date:  1981-10       Impact factor: 3.840

5.  The matrix metalloproteinase 9 (mmp-9) hemopexin domain is a novel gelatin binding domain and acts as an antagonist.

Authors:  Elke Roeb; Karin Schleinkofer; Thomas Kernebeck; Stephan Pötsch; Bettina Jansen; Iris Behrmann; Siegfried Matern; Joachim Grötzinger
Journal:  J Biol Chem       Date:  2002-10-15       Impact factor: 5.157

6.  X-linked amelogenesis imperfecta may result from decreased formation of tyrosine rich amelogenin peptide (TRAP).

Authors:  Wu Li; Cen Gao; Yan Yan; Pamela DenBesten
Journal:  Arch Oral Biol       Date:  2003-03       Impact factor: 2.633

7.  Amelogenin post-translational modifications: carboxy-terminal processing and the phosphorylation of bovine and porcine "TRAP" and "LRAP" amelogenins.

Authors:  A G Fincham; J Moradian-Oldak
Journal:  Biochem Biophys Res Commun       Date:  1993-11-30       Impact factor: 3.575

Review 8.  Proline-dependent structural and biological properties of peptides and proteins.

Authors:  A Yaron; F Naider
Journal:  Crit Rev Biochem Mol Biol       Date:  1993       Impact factor: 8.250

9.  Specific cleavage of a recombinant murine amelogenin at the carboxy-terminal region by a proteinase fraction isolated from developing bovine tooth enamel.

Authors:  J Moradian-Oldak; J P Simmer; P E Sarte; M Zeichner-David; A G Fincham
Journal:  Arch Oral Biol       Date:  1994-08       Impact factor: 2.633

10.  Sequential hydrolysis of proline-containing peptides with immobilized aminopeptidases.

Authors:  G Fleminger; A Yaron
Journal:  Biochim Biophys Acta       Date:  1983-03-30
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  10 in total

1.  Perturbed amelogenin secondary structure leads to uncontrolled aggregation in amelogenesis imperfecta mutant proteins.

Authors:  Rajamani Lakshminarayanan; Keith M Bromley; Ya-Ping Lei; Malcolm L Snead; Janet Moradian-Oldak
Journal:  J Biol Chem       Date:  2010-10-07       Impact factor: 5.157

2.  Mmp-20 and Klk4 cleavage site preferences for amelogenin sequences.

Authors:  T Nagano; A Kakegawa; Y Yamakoshi; S Tsuchiya; J C-C Hu; K Gomi; T Arai; J D Bartlett; J P Simmer
Journal:  J Dent Res       Date:  2009-09       Impact factor: 6.116

3.  Folding, assembly, and aggregation of recombinant murine amelogenins with T21I and P41T point mutations.

Authors:  Keith M Bromley; Rajamani Lakshminarayanan; Ya-Ping Lei; Malcolm L Snead; Janet Moradian-Oldak
Journal:  Cells Tissues Organs       Date:  2011-05-02       Impact factor: 2.481

4.  Amelogenin and enamelysin localization in human dental germs.

Authors:  Francisco Javier Gutiérrez-Cantú; Alfredo Feria-Velasco; Laura Nayeli Palacios-Arenas; Keila Neri Alvarado-Estrada; Francisco Javier Avelar-González; Héctor Flores-Reyes; Jairo Mariel-Cárdenas; Alma Lilián Guerrero-Barrera
Journal:  In Vitro Cell Dev Biol Anim       Date:  2011-04-21       Impact factor: 2.416

5.  Prospects and Pits on the Path of Biomimetics: The case of tooth enamel.

Authors:  Vuk Uskoković
Journal:  J Biomim Biomater Tissue Eng       Date:  2010-11

6.  Altered self-assembly and apatite binding of amelogenin induced by N-terminal proline mutation.

Authors:  Li Zhu; Vuk Uskoković; Thuan Le; Pamela Denbesten; Yulei Huang; Stefan Habelitz; Wu Li
Journal:  Arch Oral Biol       Date:  2011-04       Impact factor: 2.633

7.  Hydrolysis of amelogenin by matrix metalloprotease-20 accelerates mineralization in vitro.

Authors:  Vuk Uskoković; Feroz Khan; Haichuan Liu; Halina Ewa Witkowska; Li Zhu; Wu Li; Stefan Habelitz
Journal:  Arch Oral Biol       Date:  2011-07-20       Impact factor: 2.633

8.  Amelogenin in Enamel Tissue Engineering.

Authors:  Vuk Uskoković
Journal:  Adv Exp Med Biol       Date:  2015       Impact factor: 2.622

9.  Mutations in the beta propeller WDR72 cause autosomal-recessive hypomaturation amelogenesis imperfecta.

Authors:  Walid El-Sayed; David A Parry; Roger C Shore; Mushtaq Ahmed; Hussain Jafri; Yasmin Rashid; Suhaila Al-Bahlani; Sharifa Al Harasi; Jennifer Kirkham; Chris F Inglehearn; Alan J Mighell
Journal:  Am J Hum Genet       Date:  2009-10-22       Impact factor: 11.025

10.  Preferential and selective degradation and removal of amelogenin adsorbed on hydroxyapatites by MMP20 and KLK4 in vitro.

Authors:  Li Zhu; Haichuan Liu; H Ewa Witkowska; Yulei Huang; Kataro Tanimoto; Wu Li
Journal:  Front Physiol       Date:  2014-07-24       Impact factor: 4.566
  10 in total

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