Literature DB >> 18433808

Anti-HIV-1 protease triterpenoids from Stauntonia obovatifoliola Hayata subsp. intermedia.

Ying Wei1, Chao-mei Ma, De-yuan Chen, Masao Hattori.   

Abstract

Three triterpenoids, 16beta-hydroxy-2,3-seco-lup-20(29)-ene-2,3-dioic acid (1), 3beta,21beta,24-trihydroxy-30-noroleana-12,20(29)-dien-28-oic acid (2) and 16beta-hydroxylupane-1,20(29)-dien-3-one (3), along with eleven known triterpenes were isolated from stems of Stauntonia obovatifoliola Hayata subsp. intermedia (Y.C. Wu) T. Chen. Their structures were determined by analysis of HR-EI/FAB-MS and 1D and 2D NMR spectroscopic data and comparison with those in the literature. Ten of the compounds showed inhibitory activity against HIV-1 protease.

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Year:  2008        PMID: 18433808     DOI: 10.1016/j.phytochem.2008.03.004

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  10 in total

Review 1.  Recent Progress in the Development of HIV-1 Protease Inhibitors for the Treatment of HIV/AIDS.

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2.  Phytochemical and biological studies of Adiantum capillus-veneris L.

Authors:  Zedan Z Ibraheim; Amany S Ahmed; Yaser G Gouda
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Review 3.  Plant-derived triterpenoids and analogues as antitumor and anti-HIV agents.

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Journal:  Acta Pharmacol Sin       Date:  2016-09-12       Impact factor: 6.150

5.  Inhibitory Activities of Stauntonia hexaphylla Leaf Constituents on Rat Lens Aldose Reductase and Formation of Advanced Glycation End Products and Antioxidant.

Authors:  Seung Hwan Hwang; Shin Hwa Kwon; Set Byeol Kim; Soon Sung Lim
Journal:  Biomed Res Int       Date:  2017-02-23       Impact factor: 3.411

Review 6.  Structure-Activity-Relationship and Mechanistic Insights for Anti-HIV Natural Products.

Authors:  Ramandeep Kaur; Pooja Sharma; Girish K Gupta; Fidele Ntie-Kang; Dinesh Kumar
Journal:  Molecules       Date:  2020-04-29       Impact factor: 4.411

7.  Enhancement of an In Vivo Anti-Inflammatory Activity of Oleanolic Acid through Glycosylation Occurring Naturally in Stauntonia hexaphylla.

Authors:  Le Ba Vinh; Nguyen Thi Minh Nguyet; Liu Ye; Gao Dan; Nguyen Viet Phong; Hoang Le Tuan Anh; Young Ho Kim; Jong Seong Kang; Seo Young Yang; Inkyu Hwang
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Review 8.  Chemical Structure and Biological Activities of Secondary Metabolites from Salicornia europaea L.

Authors:  Sojeong Kim; Eun-Young Lee; Prima F Hillman; Jaeyoung Ko; Inho Yang; Sang-Jip Nam
Journal:  Molecules       Date:  2021-04-13       Impact factor: 4.411

Review 9.  Medicinal Plants Used in the Treatment of Human Immunodeficiency Virus.

Authors:  Bahare Salehi; Nanjangud V Anil Kumar; Bilge Şener; Mehdi Sharifi-Rad; Mehtap Kılıç; Gail B Mahady; Sanja Vlaisavljevic; Marcello Iriti; Farzad Kobarfard; William N Setzer; Seyed Abdulmajid Ayatollahi; Athar Ata; Javad Sharifi-Rad
Journal:  Int J Mol Sci       Date:  2018-05-14       Impact factor: 5.923

10.  Triterpenoids from Ocimum labiatum Activates Latent HIV-1 Expression In Vitro: Potential for Use in Adjuvant Therapy.

Authors:  Petrina Kapewangolo; Justin J Omolo; Pascaline Fonteh; Martha Kandawa-Schulz; Debra Meyer
Journal:  Molecules       Date:  2017-10-13       Impact factor: 4.411

  10 in total

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