Mark B Abelson1, Paul J Gomes. 1. Schepens Eye Research Institute, Boston, Massachusetts, USA. abelson@vision.eri.harvard.edu
Abstract
BACKGROUND: Olopatadine 0.2% is the first topical ophthalmic antihistamine/mast cell stabilizer indicated for once-daily dosing. OBJECTIVE: This review provides a comprehensive description of the pharmacology of the olopatadine molecule, as well as of the clinical efficacy, tolerability, and safety of olopatadine 0.2% ophthalmic solution. METHODS: References cited in this review were obtained from the PubMed biomedical literature database. Also included were several posters presented at nationally renowned ophthalmology-related conferences. RESULTS/ CONCLUSION: Olopatadine 0.2% was found to be a safe and effective medication for the reduction of itching with a duration of action of up to 24 h. The added convenience of a once-a-day dosing regimen is a major advancement in this drug class.
BACKGROUND:Olopatadine 0.2% is the first topical ophthalmic antihistamine/mast cell stabilizer indicated for once-daily dosing. OBJECTIVE: This review provides a comprehensive description of the pharmacology of the olopatadine molecule, as well as of the clinical efficacy, tolerability, and safety of olopatadine 0.2% ophthalmic solution. METHODS: References cited in this review were obtained from the PubMed biomedical literature database. Also included were several posters presented at nationally renowned ophthalmology-related conferences. RESULTS/ CONCLUSION:Olopatadine 0.2% was found to be a safe and effective medication for the reduction of itching with a duration of action of up to 24 h. The added convenience of a once-a-day dosing regimen is a major advancement in this drug class.
Authors: John D Sheppard; Melissa M Toyos; John H Kempen; Paramjit Kaur; C Stephen Foster Journal: Invest Ophthalmol Vis Sci Date: 2014-05-06 Impact factor: 4.799
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