Literature DB >> 18433163

The strong MRI relaxivity of paramagnetic nanoparticles.

Gengmei Xing1, Hui Yuan, Rui He, Xueyun Gao, Long Jing, Feng Zhao, Zhifang Chai, Yuliang Zhao.   

Abstract

We developed a method to synthesize paramagnetic nanoparticles of Gd@C82(OH)22+/-2. Such nanoparticles are with ordered microstructures and have strong MRI proton relaxation in vitro/vivo. Compared with commercial Gd-DTPA, a 12x MRI relaxivity of Gd@C82(OH)22+/-2 nanoparticles with ordered microstructures was achieved in vitro. The small Gd@C82(OH)22+/-2 nanoparticles, approximately 65nm, could easily escape the RES uptake in vivo; this opens the door for their clinical applications.

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Year:  2008        PMID： 18433163     DOI： 10.1021/jp8012706

Source DB:  PubMed          Journal:  J Phys Chem B        ISSN： 1520-5207            Impact factor:   2.991


  5 in total

1.  Metallofullerene nanoparticles circumvent tumor resistance to cisplatin by reactivating endocytosis.

Authors:  Xing-Jie Liang; Huan Meng; Yingze Wang; Haiyong He; Jie Meng; Juan Lu; Paul C Wang; Yuliang Zhao; Xueyun Gao; Baoyun Sun; Chunying Chen; Genmei Xing; Dingwu Shen; Michael M Gottesman; Yan Wu; Jun-Jie Yin; Lee Jia
Journal:  Proc Natl Acad Sci U S A       Date:  2010-04-05       Impact factor: 11.205

2.  Gadolinium metallofullerenol nanoparticles inhibit cancer metastasis through matrix metalloproteinase inhibition: imprisoning instead of poisoning cancer cells.

Authors:  Huan Meng; Gengmei Xing; Elvin Blanco; Yan Song; Lina Zhao; Baoyun Sun; Xiaoda Li; Paul C Wang; Alexandru Korotcov; Wei Li; Xing-Jie Liang; Chunying Chen; Hui Yuan; Feng Zhao; Zhen Chen; Tong Sun; Zhifang Chai; Mauro Ferrari; Yuliang Zhao
Journal:  Nanomedicine       Date:  2011-09-17       Impact factor: 5.307

3.  Synthesis and Electrochemistry of New Furylpyrazolino[60]fullerene Derivatives by Efficient Microwave Radiation.

Authors:  Hamad M Al-Matar; Mohammad H BinSabt; Mona A Shalaby
Journal:  Molecules       Date:  2019-12-04       Impact factor: 4.411

4.  The scavenging of reactive oxygen species and the potential for cell protection by functionalized fullerene materials.

Authors:  Jun-Jie Yin; Fang Lao; Peter P Fu; Wayne G Wamer; Yuliang Zhao; Paul C Wang; Yang Qiu; Baoyun Sun; Gengmei Xing; Jinquan Dong; Xing-Jie Liang; Chunying Chen
Journal:  Biomaterials       Date:  2008-11-04       Impact factor: 12.479

5.  A platform for specific delivery of lanthanide-scandium mixed-metal cluster fullerenes into target cells.

Authors:  Anna Svitova; Klaus Braun; Alexey A Popov; Lothar Dunsch
Journal:  ChemistryOpen       Date:  2012-09-28       Impact factor: 2.911
  5 in total

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