Literature DB >> 18432539

Giant cell arteritis presenting with cotton wool spots.

Michael C Johnson1, Andrew G Lee.   

Abstract

INTRODUCTION: Giant cell arteritis is a granulomatous arteritis that often presents to ophthalmology.
METHODS: Case report.
RESULTS: A 69-year-old female presented with moderate vision loss OD after suffering from severe, generalized head and neck pain over the previous 3 months. Fundus examination revealed multifocal cotton wool patches in the posterior pole surrounding the optic disc. A fluorescein angiogram OD demonstrated a large peripapillary choroidal filling defect. Erythrocyte sedimentation rate was 86 mm/hr and her C-reactive protein was 9.2 mg/dL. She was immediately started on intravenous corticosteroid therapy, and she noted rapid improvement of her symptoms. A temporal artery biopsy was positive for giant cell arteritis.
CONCLUSION: Ophthalmologists should be aware that cotton wool patches may be the presenting sign of giant cell arteritis. Fluorescein angiography may be helpful in these cases to demonstrate concomitant choroidal ischemia.

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Year:  2008        PMID: 18432539     DOI: 10.1080/08820530801946903

Source DB:  PubMed          Journal:  Semin Ophthalmol        ISSN: 0882-0538            Impact factor:   1.975


  2 in total

1.  Cotton-wool spots in giant cell arteritis.

Authors:  Elisabeth De Smit; Eoin O'Sullivan
Journal:  CMAJ       Date:  2012-10-09       Impact factor: 8.262

Review 2.  Giant cell arteritis: ophthalmic manifestations of a systemic disease.

Authors:  Elisabeth De Smit; Eoin O'Sullivan; David A Mackey; Alex W Hewitt
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2016-08-05       Impact factor: 3.117

  2 in total

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