Literature DB >> 18430261

Adult cystic hygroma: successful use of OK-432 (Picibanil).

S L Woolley1, D R K Smith, S Quine.   

Abstract

OBJECTIVE: We report an adult case of cystic lymphangioma treated with OK-432 (Picibanil).
METHOD: A case report and review of the literature concerning the use of OK-432 to treat cystic lymphangioma is presented.
RESULTS: A 31-year-old woman developed a cystic lymphangioma four weeks post-partum. This was treated initially by aspiration, for diagnostic purposes. Investigation suggested that surgery would be challenging. A review of the literature demonstrated success with OK-432 in the treatment of this condition, although primarily in the paediatric population. This patient was successfully treated thus, and at the time of writing remained symptom free. A suggested management plan is outlined.
CONCLUSION: Treatment with OK-432 is useful in the management of cystic lymphangiomas in adults and should be considered as first line treatment.

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Year:  2008        PMID: 18430261     DOI: 10.1017/S0022215107001132

Source DB:  PubMed          Journal:  J Laryngol Otol        ISSN: 0022-2151            Impact factor:   1.469


  2 in total

1.  Dysregulation of Amphiregulin stimulates the pathogenesis of cystic lymphangioma.

Authors:  Naofumi Yoshida; Seiji Yamamoto; Takeru Hamashima; Noriko Okuno; Naruho Okita; Shinjiro Horikawa; Masao Hayashi; Thanh Chung Dang; Quang Linh Nguyen; Koichi Nishiyama; Teruhiko Makino; Yoko Ishii; Kei Tomihara; Tadamichi Shimizu; Masabumi Shibuya; Makoto Noguchi; Masakiyo Sasahara
Journal:  Proc Natl Acad Sci U S A       Date:  2021-05-11       Impact factor: 11.205

2.  The bacterial preparation OK432 induces IL-12p70 secretion in human dendritic cells in a TLR3 dependent manner.

Authors:  Arnt-Ove Hovden; Marie Karlsen; Roland Jonsson; Silke Appel
Journal:  PLoS One       Date:  2012-02-21       Impact factor: 3.240

  2 in total

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