Clinical and histopathologic study of pilomatricoma in Iran between 1992 and 2005.

Pilomatricoma (calcifying epithelioma of Malherb) is a tumor of hair follicle matrix cells and is almost always benign. In this study we reviewed the clinical and histopathological features of 45 cases of pilomatricoma during 13 years (1992-2005). Although few malignant transformations have been reported in other studies, no evidence of malignancy or aggressiveness is observed in this study.