| Literature DB >> 18429619 |
Abstract
A complex formed in situ from Er(OTf)3 and a simple commercially available norephedrine ligand promotes an unprecedented [4 + 2] cycloaddition of alpha,beta-unsaturated acid chlorides with a broad range of aromatic and heteroaromatic aldehydes by a cooperative bifunctional Lewis acid-Lewis base catalytic mode of action providing valuable delta-lactone building blocks with excellent enantioselectivity.Entities:
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Year: 2008 PMID： 18429619 DOI： 10.1021/ol800742d
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005