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Literature DB >> 18429164

Overview of pepsin-like aspartic peptidases.

Abstract

The aspartic peptidase family of enzymes has been implicated in a variety of disease states, from stomach ulcers, to breast cancer, and even Alzheimer's Disease. This unit describes the major characteristics of the aspartic peptidases, including mechanism of action, subcellular and tissue localization, and biological substrate specificity.

Entities: Disease

Mesh：

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Year: 2001 PMID： 18429164 DOI： 10.1002/0471140864.ps2103s25

Source DB: PubMed Journal: Curr Protoc Protein Sci ISSN： 1934-3655

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Cited

13 in total

1. Influence of salting process on the structure and in vitro digestibility of actomyosin.

Authors: Di Zhao; Jing He; Xiaoyu Zou; Yingqun Nian; Xianglian Xu; Guanghong Zhou; Chunbao Li
Journal: J Food Sci Technol Date: 2019-12-13 Impact factor: 2.701

2. Optimal Feeding Frequency for Captive Hawksbill Sea Turtle (Eretmochelys imbricata).

Authors: Suthep Jualaong; Hirun Kanghae; Karun Thongprajukaew; Suktianchai Saekhow; Natthida Amartiratana; Piyanan Sotong
Journal: Animals (Basel) Date: 2021-04-26 Impact factor: 2.752

3. Pulsed Hydrogen-Deuterium Exchange Reveals Altered Structures and Mechanisms in the Aggregation of Familial Alzheimer's Disease Mutants.

Authors: Eva Illes-Toth; Georg Meisl; Don L Rempel; Tuomas P J Knowles; Michael L Gross
Journal: ACS Chem Neurosci Date: 2021-05-14 Impact factor: 5.780

4. Trypsin potentiates human fibrocyte differentiation.

Authors: Michael J V White; Melissa Glenn; Richard H Gomer
Journal: PLoS One Date: 2013-08-07 Impact factor: 3.240

5. Integrated Activity and Genetic Profiling of Secreted Peptidases in Cryptococcus neoformans Reveals an Aspartyl Peptidase Required for Low pH Survival and Virulence.

Authors: Starlynn C Clarke; Phillip A Dumesic; Christina M Homer; Anthony J O'Donoghue; Florencia La Greca; Lenka Pallova; Pavel Majer; Hiten D Madhani; Charles S Craik
Journal: PLoS Pathog Date: 2016-12-15 Impact factor: 6.823

6. In Silico Analysis of Bioactive Peptides Released from Giant Grouper (Epinephelus lanceolatus) Roe Proteins Identified by Proteomics Approach.

Authors: Fenny Crista A Panjaitan; Honey Lyn R Gomez; Yu-Wei Chang
Journal: Molecules Date: 2018-11-08 Impact factor: 4.411

Overview of pepsin-like aspartic peptidases.

1. Influence of salting process on the structure and in vitro digestibility of actomyosin.

2. Optimal Feeding Frequency for Captive Hawksbill Sea Turtle (Eretmochelys imbricata).

3. Pulsed Hydrogen-Deuterium Exchange Reveals Altered Structures and Mechanisms in the Aggregation of Familial Alzheimer's Disease Mutants.

4. Trypsin potentiates human fibrocyte differentiation.

5. Integrated Activity and Genetic Profiling of Secreted Peptidases in Cryptococcus neoformans Reveals an Aspartyl Peptidase Required for Low pH Survival and Virulence.

6. In Silico Analysis of Bioactive Peptides Released from Giant Grouper (Epinephelus lanceolatus) Roe Proteins Identified by Proteomics Approach.

7. Structure-function analysis of Sedolisins: evolution of tripeptidyl peptidase and endopeptidase subfamilies in fungi.

8. Bioinformatic flowchart and database to investigate the origins and diversity of clan AA peptidases.

9. Effect of High Pressure on the Porcine Placenral Hydrolyzing Activity of Pepsin, Trypsin and Chymotrypsin.

10. Evolutionary Selection on Barrier Activity: Bar1 Is an Aspartyl Protease with Novel Substrate Specificity.