Literature DB >> 18428961

Synthesis of ribonucleosides by condensation using trimethylsilyl triflate.

Helmut Vorbrüggen1, Irene M Lagoja, Piet Herdewijn.   

Abstract

This unit describes, in detail, the optimized condition for the synthesis of nucleosides making use of the trimethysilyl triflate-mediated silyl-Hilbert-Johnson synthesis. This unit focuses on the mechanistic understanding of this universal and conveniently applicable method.

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Year:  2007        PMID: 18428961     DOI: 10.1002/0471142700.nc0113s27

Source DB:  PubMed          Journal:  Curr Protoc Nucleic Acid Chem        ISSN: 1934-9270


  2 in total

1.  Enzymatic separation of epimeric 4-C-hydroxymethylated furanosugars: Synthesis of bicyclic nucleosides.

Authors:  Neha Rana; Manish Kumar; Vinod Khatri; Jyotirmoy Maity; Ashok K Prasad
Journal:  Beilstein J Org Chem       Date:  2017-10-05       Impact factor: 2.883

2.  Synthesis and Antiviral Activity of a Series of 2'-C-Methyl-4'-thionucleoside Monophosphate Prodrugs.

Authors:  Zackery W Dentmon; Thomas M Kaiser; Dennis C Liotta
Journal:  Molecules       Date:  2020-11-06       Impact factor: 4.411

  2 in total

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