Literature DB >> 18428554

Rodent models of focal cerebral ischemia.

M J O'Neill1, J A Clemens.   

Abstract

This unit presents models that are both used to study ischemic mechanisms and to test for neuroprotective agents or agents that enhance recovery from stroke. The Tamura model is one of the best characterized focal ischemia models in which the middle cerebral artery is occluded by electrocoagulation. Also described is the intraluminal monofilament model, the spontaneously hypertensive rat (SHR), and the newer endothelin-1 model. The rationale behind the use of animal models, the various types of models and advantage and disadvantages of each model are presented.

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Year:  2001        PMID： 18428554     DOI： 10.1002/0471142301.ns0906s12

Source DB:  PubMed          Journal:  Curr Protoc Neurosci        ISSN： 1934-8576


  6 in total

1.  Endothelin-1 induced middle cerebral artery occlusion model for ischemic stroke with laser Doppler flowmetry guidance in rat.

Authors:  Saeed Ansari; Hassan Azari; Kenneth J Caldwell; Robert W Regenhardt; Vishnumurthy S Hedna; Micheal F Waters; Brian L Hoh; Adam P Mecca
Journal:  J Vis Exp       Date:  2013-02-16       Impact factor: 1.355

2.  Bystander Effect Fuels Human Induced Pluripotent Stem Cell-Derived Neural Stem Cells to Quickly Attenuate Early Stage Neurological Deficits After Stroke.

Authors:  Auston Eckert; Lei Huang; Rodolfo Gonzalez; Hye-Sun Kim; Milton H Hamblin; Jean-Pyo Lee
Journal:  Stem Cells Transl Med       Date:  2015-05-29       Impact factor: 6.940

3.  Application time and persistence of transcranial direct current stimulation (tDCS) against neuronal death resulting from transient cerebral ischemia.

Authors:  Jong-Hun Lee; Bo Hyun Jung; Ki-Yeon Yoo
Journal:  Lab Anim Res       Date:  2022-05-08

4.  Human neural stem cells rapidly ameliorate symptomatic inflammation in early-stage ischemic-reperfusion cerebral injury.

Authors:  Lei Huang; Sunnie Wong; Evan Y Snyder; Milton H Hamblin; Jean-Pyo Lee
Journal:  Stem Cell Res Ther       Date:  2014-11-23       Impact factor: 6.832

Review 5.  The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments).

Authors:  Nathalie Percie du Sert; Alessio Alfieri; Stuart M Allan; Hilary Vo Carswell; Graeme A Deuchar; Tracy D Farr; Paul Flecknell; Lindsay Gallagher; Claire L Gibson; Michael J Haley; Malcolm R Macleod; Barry W McColl; Christopher McCabe; Anna Morancho; Lawrence Df Moon; Michael J O'Neill; Isabel Pérez de Puig; Anna Planas; C Ian Ragan; Anna Rosell; Lisa A Roy; Kathryn O Ryder; Alba Simats; Emily S Sena; Brad A Sutherland; Mark D Tricklebank; Rebecca C Trueman; Lucy Whitfield; Raymond Wong; I Mhairi Macrae
Journal:  J Cereb Blood Flow Metab       Date:  2017-08-11       Impact factor: 6.200

Review 6.  Translational Stroke Research Review: Using the Mouse to Model Human Futile Recanalization and Reperfusion Injury in Ischemic Brain Tissue.

Authors:  Emilia Conti; Benedetta Piccardi; Alessandro Sodero; Laura Tudisco; Ivano Lombardo; Enrico Fainardi; Patrizia Nencini; Cristina Sarti; Anna Letizia Allegra Mascaro; Marzia Baldereschi
Journal:  Cells       Date:  2021-11-25       Impact factor: 6.600
  6 in total

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