| Literature DB >> 18428358 |
Jerry B Dodgson1, Michael N Romanov.
Abstract
The chicken has been a valuable model organism for genetic analysis since early in the last century. This unit provides an overview of the primary strategic approaches through which the chicken is used as a model for human genetics and disease. These approaches are reviewed with key advantages and disadvantages noted for each. In addition, the chicken offers a model system for several human inherited diseases, both single gene-based and complex traits. This unit briefly describes two such models as examples: autoimmune pathology causing Hashimoto's thyroiditis and sex-linked dwarfism.Entities:
Mesh:
Year: 2004 PMID: 18428358 DOI: 10.1002/0471142905.hg1505s40
Source DB: PubMed Journal: Curr Protoc Hum Genet ISSN: 1934-8258