| Literature DB >> 18425564 |
Naoto Azuma1, Yoshinori Katada, Nobumasa Nishimura, Tomonori Yamada, Ryunosuke Uranishi, Shinichi Nakatsuka, Makoto Dehara, Yoshinori Harada, Takao Yamanaka, Yukihiko Saeki.
Abstract
We report a case of Wegener's granulomatosis (WG) with central nervous system (CNS) involvement in a woman who complained of bilateral visual disturbance. The intracranial necrotizing granulomatous lesion was confirmed by MR imaging and brain biopsy. After high-dose oral corticosteroid treatment, not only clinical manifestations but also laboratory tests improved. Moreover, the CNS lesion completely regressed. This suggests that high-dose corticosteroid alone might be effective in treating WG with CNS involvement.Entities:
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Year: 2008 PMID： 18425564 DOI： 10.1007/s10165-008-0070-z
Source DB: PubMed Journal: Mod Rheumatol ISSN： 1439-7595 Impact factor: 3.023