Literature DB >> 18423511

Protanomaly without darkened red is deuteranopia with rods.

Steven K Shevell1, Yang Sun, Maureen Neitz.   

Abstract

The Rayleigh match, a color match between a mixture of 545+670 nm lights and 589 nm light in modern instruments, is the definitive measurement for the diagnosis of inherited red-green color defects. All trichromats, whether normal or anomalous, have a limited range of 545+670 nm mixtures they perceive to match 589 nm: a typical color-normal match range is about 50-55% of 670 nm in the mixture (deutan mode), while deuteranomals have a range that includes mixtures with less 670 nm than normal and protanomals a range that includes mixtures with more 670 nm than normal. Further, the matching luminance of the 589 nm light for deuteranomals is the same as for normals but for protanomals is below normal. An example of an unexpected Rayleigh match, therefore, is a match range above normal (typical of protanomaly) and a normal luminance setting for 589 nm (typical of deuteranomaly), a match called protanomaly "when the red end of the spectrum is not darkened" [Pickford, R.W. (1950). Three pedigrees for color blindness. Nature, 165, 182.]. In this case, Rayleigh matching does not yield a clear diagnosis. Aside from Pickford, we are aware of only one other report of a similar observer [Pokorny, J., & Smith, V. C. (1981). A variant of red-green color defect. Vision Research, 21, 311-317]; this study predated modern genetic techniques that can reveal the cone photopigment(s) in the red-green range. We recently had the opportunity to conduct genetic and psychophysical tests on such an observer. Genetic results predict he is a deuteranope. His Rayleigh match is consistent with L cones and a contribution from rods. Further, with a rod-suppressing background, his Rayleigh match is characteristic of a single L-cone photopigment (deuteranopia).

Entities:  

Mesh:

Substances:

Year:  2008        PMID: 18423511      PMCID: PMC2596756          DOI: 10.1016/j.visres.2008.03.001

Source DB:  PubMed          Journal:  Vision Res        ISSN: 0042-6989            Impact factor:   1.886


  15 in total

1.  Estimates of L:M cone ratio from ERG flicker photometry and genetics.

Authors:  Joseph Carroll; Jay Neitz; Maureen Neitz
Journal:  J Vis       Date:  2002       Impact factor: 2.240

2.  Evidence of photoreceptor migration during early foveal development: a quantitative analysis of human fetal retinae.

Authors:  C Diaz-Araya; J M Provis
Journal:  Vis Neurosci       Date:  1992-06       Impact factor: 3.241

3.  Three pedigrees for colour blindness.

Authors:  R W PICKFORD
Journal:  Nature       Date:  1950-01-14       Impact factor: 49.962

4.  Large-field trichromacy in protanopes and deuteranopes.

Authors:  V C Smith; J Pokorny
Journal:  J Opt Soc Am       Date:  1977-02

5.  Color perception under chromatic adaptation: red/green equilibria with adapted short-wavelength-sensitive cones.

Authors:  S K Shevell; R A Humanski
Journal:  Vision Res       Date:  1988       Impact factor: 1.886

6.  Derivation of the photopigment absorption spectra in anomalous trichromats.

Authors:  J Pokorny; V C Smith; I Katz
Journal:  J Opt Soc Am       Date:  1973-02

7.  Visual pigments in dichromats.

Authors:  D E Mitchell; W A Rushton
Journal:  Vision Res       Date:  1971-10       Impact factor: 1.886

8.  A variant of red-green color defect.

Authors:  J Pokorny; V C Smith
Journal:  Vision Res       Date:  1981       Impact factor: 1.886

9.  Molecular genetics of human color vision: the genes encoding blue, green, and red pigments.

Authors:  J Nathans; D Thomas; D S Hogness
Journal:  Science       Date:  1986-04-11       Impact factor: 47.728

10.  Variation in color matching and discrimination among deuteranomalous trichromats: theoretical implications of small differences in photopigments.

Authors:  J C He; S K Shevell
Journal:  Vision Res       Date:  1995-09       Impact factor: 1.886

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.