Literature DB >> 18423456

Pretreatment with gonadotropin-releasing hormone (GnRH) antagonists to prevent the flare-up effect of long-acting GnRH agonists: results of a pilot study.

Andreas Mueller1, Theodoros Maltaris, Lothar Häberle, Inge Hoffmann, Matthias W Beckmann, Ralf Dittrich.   

Abstract

This study evaluated in vivo whether the flare-up effect of GnRH agonists can be suppressed through pretreatment with a GnRH antagonist. The classic flare-up effect caused by 3.8 mg goserelin acetate could not be suppressed through pretreatment using a single dosage of 3.24 mg cetrorelix acetate.

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Year:  2008        PMID： 18423456     DOI： 10.1016/j.fertnstert.2007.11.066

Source DB:  PubMed          Journal:  Fertil Steril        ISSN： 0015-0282            Impact factor:   7.329


  2 in total

1.  Recurrent Cerebral Infarcts Associated with Uterine Adenomyosis: Successful Prevention by Surgical Removal.

Authors:  Manato Yasuda; Yoshitaka Yamanaka; Hiroki Kano; Nobuyuki Araki; Hiroshi Ishikawa; Jun-Ichiro Ikeda; Satoshi Kuwabara
Journal:  Intern Med       Date:  2021-09-04       Impact factor: 1.271

2.  Combination of a GnRH agonist with an antagonist prevents flare-up effects and protects primordial ovarian follicles in the rat ovary from cisplatin-induced toxicity: a controlled experimental animal study.

Authors:  Xiaoyan Li; Xiang Kang; Qingchun Deng; Jing Cai; Zehua Wang
Journal:  Reprod Biol Endocrinol       Date:  2013-03-01       Impact factor: 5.211
  2 in total

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