Literature DB >> 18423199

Meiosis I is established through division-specific translational control of a cyclin.

Thomas M Carlile1, Angelika Amon.   

Abstract

In budding yeast, key meiotic events such as DNA replication, recombination, and the meiotic divisions are controlled by Clb cyclin-dependent kinases (Clb-CDKs). Using a novel synchronization procedure, we have characterized the activity of these Clb-CDKs and observed a surprising diversity in their regulation during the meiotic divisions. Clb1-CDK activity is restricted to meiosis I, and Clb3-CDK activity to meiosis II, through 5'UTR-mediated translational control of its transcript. The analysis of cells inappropriately producing Clb3-CDKs during meiosis I furthermore defines Clb3 as an inhibitor of the meiosis I chromosome segregation program. Our results demonstrate an essential role for Clb-CDK regulation in establishing the meiotic chromosome segregation pattern.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 18423199      PMCID： PMC2396536          DOI： 10.1016/j.cell.2008.02.032

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  38 in total

1.  Control of landmark events in meiosis by the CDK Cdc28 and the meiosis-specific kinase Ime2.

Authors:  Kirsten R Benjamin; Chao Zhang; Kevan M Shokat; Ira Herskowitz
Journal:  Genes Dev       Date:  2003-06-03       Impact factor: 11.361

2.  Destruction of the securin Pds1p occurs at the onset of anaphase during both meiotic divisions in yeast.

Authors:  S M Salah; K Nasmyth
Journal:  Chromosoma       Date:  2000       Impact factor: 4.316

3.  Requirement of the spindle checkpoint for proper chromosome segregation in budding yeast meiosis.

Authors:  M A Shonn; R McCarroll; A W Murray
Journal:  Science       Date:  2000-07-14       Impact factor: 47.728

4.  A potential positive feedback loop controlling CLN1 and CLN2 gene expression at the start of the yeast cell cycle.

Authors:  F R Cross; A H Tinkelenberg
Journal:  Cell       Date:  1991-05-31       Impact factor: 41.582

5.  Role of Polo-like kinase CDC5 in programming meiosis I chromosome segregation.

Authors:  Brian H Lee; Angelika Amon
Journal:  Science       Date:  2003-03-27       Impact factor: 47.728

6.  Division of the nucleolus and its release of CDC14 during anaphase of meiosis I depends on separase, SPO12, and SLK19.

Authors:  Sara B C Buonomo; Kirsten P Rabitsch; Jörg Fuchs; Stephan Gruber; Matt Sullivan; Frank Uhlmann; Mark Petronczki; Attila Tóth; Kim Nasmyth
Journal:  Dev Cell       Date:  2003-05       Impact factor: 12.270

7.  The Cdc14 phosphatase and the FEAR network control meiotic spindle disassembly and chromosome segregation.

Authors:  Adele L Marston; Brian H Lee; Angelika Amon
Journal:  Dev Cell       Date:  2003-05       Impact factor: 12.270

8.  Spo13 protects meiotic cohesin at centromeres in meiosis I.

Authors:  Marion A Shonn; Robert McCarroll; Andrew W Murray
Journal:  Genes Dev       Date:  2002-07-01       Impact factor: 11.361

9.  The role of phosphorylation and the CDC28 protein kinase in cell cycle-regulated nuclear import of the S. cerevisiae transcription factor SWI5.

Authors:  T Moll; G Tebb; U Surana; H Robitsch; K Nasmyth
Journal:  Cell       Date:  1991-08-23       Impact factor: 41.582

10.  SPO13 negatively regulates the progression of mitotic and meiotic nuclear division in Saccharomyces cerevisiae.

Authors:  R M McCarroll; R E Esposito
Journal:  Genetics       Date:  1994-09       Impact factor: 4.562
View more
  129 in total

1.  Phosphorylation-Mediated Clearance of Amyloid-like Assemblies in Meiosis.

Authors:  Kayla Carpenter; Rachel Brietta Bell; Julius Yunus; Angelika Amon; Luke Edwin Berchowitz
Journal:  Dev Cell       Date:  2018-05-07       Impact factor: 12.270

2.  Predicted RNA Binding Proteins Pes4 and Mip6 Regulate mRNA Levels, Translation, and Localization during Sporulation in Budding Yeast.

Authors:  Liang Jin; Kai Zhang; Rolf Sternglanz; Aaron M Neiman
Journal:  Mol Cell Biol       Date:  2017-04-14       Impact factor: 4.272

3.  Cdc7-Dbf4 regulates NDT80 transcription as well as reductional segregation during budding yeast meiosis.

Authors:  Hsiao-Chi Lo; Lihong Wan; Adam Rosebrock; Bruce Futcher; Nancy M Hollingsworth
Journal:  Mol Biol Cell       Date:  2008-09-03       Impact factor: 4.138

4.  The Aurora kinase Ipl1 is necessary for spindle pole body cohesion during budding yeast meiosis.

Authors:  Katelan Shirk; Hui Jin; Thomas H Giddings; Mark Winey; Hong-Guo Yu
Journal:  J Cell Sci       Date:  2011-09-01       Impact factor: 5.285

5.  The multiple roles of cohesin in meiotic chromosome morphogenesis and pairing.

Authors:  Gloria A Brar; Andreas Hochwagen; Ly-sha S Ee; Angelika Amon
Journal:  Mol Biol Cell       Date:  2008-12-10       Impact factor: 4.138

6.  Transcriptional repression of CDC6 and SLD2 during meiosis is associated with production of short heterogeneous RNA isoforms.

Authors:  David V Phizicky; Stephen P Bell
Journal:  Chromosoma       Date:  2018-10-01       Impact factor: 4.316

7.  Kinetochore inactivation by expression of a repressive mRNA.

Authors:  Jingxun Chen; Amy Tresenrider; Minghao Chia; David T McSwiggen; Gianpiero Spedale; Victoria Jorgensen; Hanna Liao; Folkert Jacobus van Werven; Elçin Ünal
Journal:  Elife       Date:  2017-09-14       Impact factor: 8.140

Review 8.  Emerging roles for centromeres in meiosis I chromosome segregation.

Authors:  Gloria A Brar; Angelika Amon
Journal:  Nat Rev Genet       Date:  2008-12       Impact factor: 53.242

Review 9.  Post-transcriptional regulation in budding yeast meiosis.

Authors:  Liang Jin; Aaron M Neiman
Journal:  Curr Genet       Date:  2015-11-27       Impact factor: 3.886

10.  Pch2 links chromosome axis remodeling at future crossover sites and crossover distribution during yeast meiosis.

Authors:  Neeraj Joshi; Aekam Barot; Christine Jamison; G Valentin Börner
Journal:  PLoS Genet       Date:  2009-07-24       Impact factor: 5.917
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.