Literature DB >> 18421756

Synthesis of resveratrol analogues, and evaluation of their cytotoxic and xanthine oxidase inhibitory activities.

Xian-Feng Huang1, Huan-Qiu Li, Lei Shi, Jia-Yu Xue, Ban-Feng Ruan, Hai-Liang Zhu.   

Abstract

Thirteen resveratrol (=5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol) analogues with a CHO group have been prepared by partial synthesis from resveratrol. The synthesized compounds have been evaluated for their cytotoxic activity against a human nasopharyngeal epidermoid tumor cell line KB, as well as for their xanthine oxidase inhibitory activity. Compounds 2, 3, and 6a showed the most significant cytotoxic activities against the cell line KB, and compound 2 also exhibited strong xanthine oxidase inhibitory activity.

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Year:  2008        PMID： 18421756     DOI： 10.1002/cbdv.200890059

Source DB:  PubMed          Journal:  Chem Biodivers        ISSN： 1612-1872            Impact factor:   2.408


  10 in total

1.  Suppression of oxidative stress by resveratrol after isometric contractions in gastrocnemius muscles of aged mice.

Authors:  Michael J Ryan; Janna R Jackson; Yanlei Hao; Courtney L Williamson; Erinne R Dabkowski; John M Hollander; Stephen E Alway
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2010-05-27       Impact factor: 6.053

2.  Empagliflozin and uric acid metabolism in diabetes: A post hoc analysis of the EMPA-REG OUTCOME trial.

Authors:  João Pedro Ferreira; Silvio E Inzucchi; Michaela Mattheus; Thomas Meinicke; Dominik Steubl; Christoph Wanner; Bernard Zinman
Journal:  Diabetes Obes Metab       Date:  2021-10-04       Impact factor: 6.408

3.  (E)-2,3-Bis(4-methoxy-phen-yl)acrylic acid.

Authors:  Banfeng Ruan; Ying Yang; Zhenwei Zhu; Pengcheng Lv; Hailiang Zhu
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-04-02

4.  Ethyl 3-(4-hydroxy-phen-oxy)-2-(4-methoxy-phen-yl)acrylate.

Authors:  Jin Hou
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-11-08

5.  Use of In Vitro and Predictive In Silico Models to Study the Inhibition of Cytochrome P4503A by Stilbenes.

Authors:  Loai Basheer; Keren Schultz; Merav Fichman; Zohar Kerem
Journal:  PLoS One       Date:  2015-10-20       Impact factor: 3.240

Review 6.  The Immunomodulatory and Anti-Inflammatory Role of Polyphenols.

Authors:  Nour Yahfoufi; Nawal Alsadi; Majed Jambi; Chantal Matar
Journal:  Nutrients       Date:  2018-11-02       Impact factor: 5.717

Review 7.  Autophagy-dependent and -independent modulation of oxidative and organellar stress in the diabetic heart by glucose-lowering drugs.

Authors:  Milton Packer
Journal:  Cardiovasc Diabetol       Date:  2020-05-13       Impact factor: 9.951

8.  Integrating cellular metabolism into a multiscale whole-body model.

Authors:  Markus Krauss; Stephan Schaller; Steffen Borchers; Rolf Findeisen; Jörg Lippert; Lars Kuepfer
Journal:  PLoS Comput Biol       Date:  2012-10-25       Impact factor: 4.475

Review 9.  Recent Advances on the Anti-Inflammatory and Antioxidant Properties of Red Grape Polyphenols: In Vitro and In Vivo Studies.

Authors:  Thea Magrone; Manrico Magrone; Matteo Antonio Russo; Emilio Jirillo
Journal:  Antioxidants (Basel)       Date:  2019-12-31

Review 10.  Micronutrients and bioactive compounds in the immunological pathways related to SARS-CoV-2 (adults and elderly).

Authors:  Juliana Arruda de Souza Monnerat; Pedro Ribeiro de Souza; Letícia Monteiro da Fonseca Cardoso; João Dario Mattos; Gabrielle de Souza Rocha; Renata Frauches Medeiros
Journal:  Eur J Nutr       Date:  2020-10-21       Impact factor: 4.865
  10 in total

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