Literature DB >> 18421506

Establishing the diagnosis of Libman-Sacks endocarditis in systemic lupus erythematosus.

Geraldine E Ménard1.   

Abstract

CASE: A 43-year-old female with systemic lupus erythematosus (SLE) was admitted with fever and shortness of breath 1 month after aortic valve replacement. A diagnostic workup including chemistries, complete blood count, blood cultures, chest x-ray, and 2-D echocardiogram was performed to determine the etiology of her symptoms and differentiate between acute bacterial endocarditis and Libman-Sacks endocarditis. DISCUSSION: By utilizing Duke's criteria, antiphospholipid antibodies, and serial echocardiography, we were able to make a diagnosis of Libman-Sacks endocarditis. The patient was successfully treated for Libman-Sacks endocarditis and recovered uneventfully.
CONCLUSION: This case highlights the challenges of making the correct diagnosis when 2 disease processes present with similar findings.

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Year:  2008        PMID: 18421506      PMCID: PMC2517866          DOI: 10.1007/s11606-008-0627-8

Source DB:  PubMed          Journal:  J Gen Intern Med        ISSN: 0884-8734            Impact factor:   5.128


  15 in total

1.  Proposed modifications to the Duke criteria for the diagnosis of infective endocarditis.

Authors:  J S Li; D J Sexton; N Mick; R Nettles; V G Fowler; T Ryan; T Bashore; G R Corey
Journal:  Clin Infect Dis       Date:  2000-04-03       Impact factor: 9.079

2.  Antiphospholipid antibodies and the heart. Lessons and pitfalls for the cardiologist.

Authors:  R A Asherson; R Cervera
Journal:  Circulation       Date:  1991-08       Impact factor: 29.690

3.  An echocardiographic study of valvular heart disease associated with systemic lupus erythematosus.

Authors:  C A Roldan; B K Shively; M H Crawford
Journal:  N Engl J Med       Date:  1996-11-07       Impact factor: 91.245

4.  High sensitivity C-reactive protein in systemic lupus erythematosus: relation to disease activity, clinical presentation and implications for cardiovascular risk.

Authors:  E V Barnes; S Narain; A Naranjo; J Shuster; M S Segal; E S Sobel; A E Armstrong; B E Santiago; W H Reeves; H B Richards
Journal:  Lupus       Date:  2005       Impact factor: 2.911

5.  Severe valvular regurgitation and antiphospholipid antibodies in systemic lupus erythematosus: a prospective, long-term, followup study.

Authors:  Felix Perez-Villa; Josep Font; Manel Azqueta; Gerard Espinosa; Carles Pare; Ricard Cervera; Joan C Reverter; Miguel Ingelmo; Gines Sanz
Journal:  Arthritis Rheum       Date:  2005-06-15

6.  Aortic insufficiency and mitral regurgitation in patients with systemic lupus erythematosus and the antiphospholipid syndrome.

Authors:  E K Chartash; D M Lans; S A Paget; T Qamar; M D Lockshin
Journal:  Am J Med       Date:  1989-04       Impact factor: 4.965

7.  Systemic lupus erythematosus valve disease by transesophageal echocardiography and the role of antiphospholipid antibodies.

Authors:  C A Roldan; B K Shively; C C Lau; F T Gurule; E A Smith; M H Crawford
Journal:  J Am Coll Cardiol       Date:  1992-11-01       Impact factor: 24.094

Review 8.  Valvular disease associated with systemic illness.

Authors:  C A Roldan
Journal:  Cardiol Clin       Date:  1998-08       Impact factor: 2.213

Review 9.  Heart valve involvement (Libman-Sacks endocarditis) in the antiphospholipid syndrome.

Authors:  M Hojnik; J George; L Ziporen; Y Shoenfeld
Journal:  Circulation       Date:  1996-04-15       Impact factor: 29.690

10.  Libman-Sacks endocarditis in systemic lupus erythematosus: prevalence, associations, and evolution.

Authors:  Ioannis Moyssakis; Maria G Tektonidou; Vassilios A Vasilliou; Michael Samarkos; Vassilios Votteas; Haralampos M Moutsopoulos
Journal:  Am J Med       Date:  2007-07       Impact factor: 4.965

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  11 in total

1.  Marantic endocarditis and paraneoplastic pulmonary embolism.

Authors:  Tiago Lobo Ferreira; Rosa Alves; Tiago Judas; Maria F Delerue
Journal:  BMJ Case Rep       Date:  2017-07-14

Review 2.  Association of antiphospholipid antibodies with valvulopathy in systemic lupus erythematosus: a systematic review.

Authors:  Priscila Mattos; Mittermayer B Santiago
Journal:  Clin Rheumatol       Date:  2011-01-05       Impact factor: 2.980

Review 3.  Valvular heart disease in antiphospholipid syndrome.

Authors:  Stéphane Zuily; Olivier Huttin; Shirine Mohamed; Pierre-Yves Marie; Christine Selton-Suty; Denis Wahl
Journal:  Curr Rheumatol Rep       Date:  2013-04       Impact factor: 4.592

Review 4.  Mitral valve surgery for mitral regurgitation caused by Libman-Sacks endocarditis: a report of four cases and a systematic review of the literature.

Authors:  Wobbe Bouma; Theo J Klinkenberg; Iwan C C van der Horst; Inez J Wijdh-den Hamer; Michiel E Erasmus; Marc Bijl; Albert J H Suurmeijer; Felix Zijlstra; Massimo A Mariani
Journal:  J Cardiothorac Surg       Date:  2010-03-23       Impact factor: 1.637

5.  Mitral Valve Perforation in Libman-Sacks Endocarditis: A Heart-Wrenching Case of Lupus.

Authors:  Elizabeth S Aby; Zachary Rosol; Mengistu A Simegn
Journal:  J Gen Intern Med       Date:  2016-03-14       Impact factor: 5.128

Review 6.  Revisiting Libman-Sacks endocarditis: a historical review and update.

Authors:  Jennifer L Lee; Stanley M Naguwa; Gurtej S Cheema; M Eric Gershwin
Journal:  Clin Rev Allergy Immunol       Date:  2009-06       Impact factor: 8.667

7.  Libman-Sacks endocarditis with an unusual presentation.

Authors:  Abdulrahman M Al-Moghairi
Journal:  J Saudi Heart Assoc       Date:  2010-06-01

8.  Multiple embolic strokes as a result of Libman-Sacks endocarditis associated with lupus and secondary antiphospholipid antibody syndrome: a case report.

Authors:  Jelena Z Arnautovic; Hiroshi Yamasaki; Howard S Rosman
Journal:  Eur Heart J Case Rep       Date:  2018-08-17

9.  Anti-nuclear antibodies positive serum from systemic lupus erythematosus patients promotes cardiovascular manifestations and the presence of human antibody in the brain.

Authors:  Marie Kelly-Worden; Leslie Hammer; Robyn Gebhard; Lauran Schrader; Marley Griffin; Dalahnna Cooper
Journal:  J Pharm Bioallied Sci       Date:  2014-07

10.  Lupus-Negative Libman-Sacks Endocarditis Complicated by Catastrophic Antiphospholipid Syndrome.

Authors:  Ghulam Murtaza; Joy Iskandar; Tara Humphrey; Sujeen Adhikari; Aneesh Kuruvilla
Journal:  Cardiol Res       Date:  2017-05-03
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