Literature DB >> 18420814

Misdiagnosis of serotonin syndrome as fibromyalgia and the role of physical therapists.

Gregory M Alnwick1.   

Abstract

BACKGROUND AND
PURPOSE: With increased use of serotonergic medications, a condition triggered by serotonin excess within the brain and spinal cord has emerged and may be gaining prevalence. The purposes of this case report are to describe how to identify serotonin syndrome in a patient who is taking citalopram (a selective serotonin reuptake inhibitor) on the basis of signs and symptoms and to promote the ability of physical therapists to recognize such signs and symptoms. CASE DESCRIPTION: The patient was a 42-year-old woman referred for physical therapy with a diagnosis of fibromyalgia. The physical therapist recognized that the patient's symptoms did not resemble those of fibromyalgia and recommended referral to a neurologist for further diagnostic testing. OUTCOMES: The patient was referred to a neurologist, who diagnosed serotonin syndrome related to the use of citalopram. The patient was weaned off citalopram and made a successful recovery, with scores on the Oswestry Disability Index decreasing from 70% to 28% at discharge from the physical therapy treatment and to 0% at the 6-month follow-up. The patient has since returned to her prior activity level, which includes skiing, motorcycle riding, and working at her consulting firm. DISCUSSION: This case report demonstrates how careful evaluation by the physical therapist indicated that signs and symptoms were not consistent with fibromyalgia, and further medical evaluation revealed the actual diagnosis of serotonin syndrome.

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Year:  2008        PMID: 18420814     DOI: 10.2522/ptj.20060208

Source DB:  PubMed          Journal:  Phys Ther        ISSN: 0031-9023


  5 in total

1.  Case Report: Schizophrenia Discovered during the Patient Interview in a Man with Shoulder Pain Referred for Physical Therapy.

Authors:  Nirtal Shah; Yuka Nakamura
Journal:  Physiother Can       Date:  2010-10-18       Impact factor: 1.037

2.  Mild serotonin syndrome: A report of 12 cases.

Authors:  Sanjay Prakash; Varsha Patel; Siddharth Kakked; Indravadan Patel; Rahul Yadav
Journal:  Ann Indian Acad Neurol       Date:  2015 Apr-Jun       Impact factor: 1.383

3.  Effectiveness of pharmacovigilance: multifaceted educational intervention related to the knowledge, skills and attitudes of multidisciplinary hospital staff.

Authors:  Fabiana Rossi Varallo; Cleopatra S Planeta; Patricia de Carvalho Mastroianni
Journal:  Clinics (Sao Paulo)       Date:  2017-01-01       Impact factor: 2.365

4.  Refining the Clinical Features of Serotonin Syndrome: A Prospective Observational Study of 45 Patients.

Authors:  Sanjay Prakash; Chaturbhuj Rathore; Kaushik Kumar Rana; Ankit Dave; Hemant Joshi; Jay Patel
Journal:  Ann Indian Acad Neurol       Date:  2019 Jan-Mar       Impact factor: 1.383

5.  Assessment and management of serotonin syndrome in a simulated patient study of Australian community pharmacies.

Authors:  Brett Macfarlane; Jenny Bergin; Gregory M Peterson
Journal:  Pharm Pract (Granada)       Date:  2016-06-15
  5 in total

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