| Literature DB >> 1842080 |
R Vince1.
Abstract
(+/-) Carbocyclic 2',3'-didehydro-2',3'-dideoxyguanosine (Carbovir) is an antiretroviral agent which is undergoing preclinical evaluation for the treatment of AIDS. Its hydrolytic stability and its ability to inhibit infectivity and replication of HIV in T-cells at concentrations of approximately 400-fold below toxic concentrations make Carbovir an excellent candidate for development as a potential antiretroviral agent.Entities:
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Year: 1991 PMID： 1842080
Source DB: PubMed Journal: Nucleic Acids Symp Ser ISSN： 0261-3166