Literature DB >> 18420134

PAK'n it in: identification of a selective PAK inhibitor.

Gary M Bokoch1.   

Abstract

p21-activated kinases are important signaling kinases for which no specific chemical inhibitors are known. In this issue of Chemistry & Biology, Deacon et al. target allosteric transitions undergone during PAK activation to identify a selective inhibitor (Deacon et al., 2008).

Entities:  

Mesh:

Substances:

Year:  2008        PMID: 18420134     DOI: 10.1016/j.chembiol.2008.03.011

Source DB:  PubMed          Journal:  Chem Biol        ISSN: 1074-5521


  1 in total

1.  Rac1 pathway mediates stretch response in pulmonary alveolar epithelial cells.

Authors:  Brian C Dipaolo; Nurit Davidovich; Marcelo G Kazanietz; Susan S Margulies
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2013-05-17       Impact factor: 5.464

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.