Literature DB >> 1842007

Bioactive glycosides from Chinese medicines.

J Zhou1.   

Abstract

Glycosides are the bioactive components of many famous Chinese medicines. Here reported are some bioactive glycosides we discovered from Chinese medicines in recent years. (1) Phenolic glycosides from Chinese medicines: Gastrodia elata, Aconitum austroyunanense and Helicia erratica, three bioactive phenolic glycosides were discovered and two of them have been developed into new drugs. (2) Terpenoidal glycosides: a) Monoterpenoid: the sweroside from Swertia moleensis has been developed into an anti-hepatitis drug; b) Diterpenoid: Phlomis betonicoides contains sweet glycosides; c) Triterpenoid: many biologically active triterpenoid glycosides were isolated from Panax plants and Siraitia grosvenorii. (3) Steroidal glycosides: a) C21-steroid: Cynanchum otophyllum and C. atratrum contain anti-epilepsy and anti-tumor glycosides; b) C27-steroid Hemostatic saponins were found in Paris polyphylla.

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Year:  1991        PMID: 1842007     DOI: 10.1590/s0074-02761991000600051

Source DB:  PubMed          Journal:  Mem Inst Oswaldo Cruz        ISSN: 0074-0276            Impact factor:   2.743


  5 in total

1.  Steroid-like compounds in Chinese medicines promote blood circulation via inhibition of Na+/K+ -ATPase.

Authors:  Ronald J Y Chen; Tse-yu Chung; Feng-yin Li; Wei-hung Yang; Tzyy-rong Jinn; Jason T C Tzen
Journal:  Acta Pharmacol Sin       Date:  2010-06       Impact factor: 6.150

Review 2.  Iridoids are natural glycation inhibitors.

Authors:  Brett J West; Shixin Deng; Akemi Uwaya; Fumiyuki Isami; Yumi Abe; Sho-Ichi Yamagishi; C Jarakae Jensen
Journal:  Glycoconj J       Date:  2016-06-15       Impact factor: 2.916

3.  Acidic polysaccharide extracts from Gastrodia Rhizomes suppress the atherosclerosis risk index through inhibition of the serum cholesterol composition in Sprague Dawley rats fed a high-fat diet.

Authors:  Kui-Jin Kim; Ok-Hwan Lee; Chan-Kyu Han; Young-Chan Kim; Hee-Do Hong
Journal:  Int J Mol Sci       Date:  2012-02-02       Impact factor: 6.208

4.  Effects of Siraitia grosvenorii Fruits Extracts on Physical Fatigue in Mice.

Authors:  Da-Duo Liu; Xue-Wu Ji; Rong-Wei Li
Journal:  Iran J Pharm Res       Date:  2013       Impact factor: 1.696

5.  Saponins From Paris forrestii (Takht.) H. Li Display Potent Activity Against Acute Myeloid Leukemia by Suppressing the RNF6/AKT/mTOR Signaling Pathway.

Authors:  Qin Lu; Yuanming He; Yuehu Wang; Li Gao; Yunjing Zheng; Zubin Zhang; Biyin Cao; Qi Wang; Xinliang Mao; Shaoyan Hu
Journal:  Front Pharmacol       Date:  2018-06-26       Impact factor: 5.810

  5 in total

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