Literature DB >> 18419364

Infection control experience in a cooperative care center for transplant patients.

Ahmad Nusair1, Dawn Jourdan, Sharon Medcalf, Nedra Marion, Peter C Iwen, Paul D Fey, Elizabeth Reed, Alan Langnas, Mark E Rupp.   

Abstract

OBJECTIVE: To characterize infection control experience during a 6.5-year period in a cooperative care center for transplant patients.
DESIGN: Descriptive analysis.
SETTING: A cooperative care center for transplanted patients, in which patients and care partners are housed in a homelike environment, and care partners assume responsibility for patient care duties. PATIENTS: Nine hundred ninety one transplant patients.
METHODS: Infection control definitions from the Centers for Disease Control and Prevention were used to ascertain infection rates. Environmental cultures were used to detect methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE), Clostridium difficile, and fungi during the first 18 months. Surveillance cultures were performed for a subset of patients and care partners.
RESULTS: From June 1999 through December 2005, there were 19,365 patient-days observed. The most common healthcare-associated infection encountered was intravascular catheter-related bloodstream infection, with infection rates of 5.74 and 4.94 cases per 1,000 patient-days for hematopoietic stem cell transplant (HSCT) and solid organ transplant (SOT) patients, respectively. C. difficile-associated diarrhea was observed more frequently in HSCT patients than in SOT patients (3.97 vs 0.57 cases per 1,000 patient-days; P < .0001). There was no evidence of environmental contamination with MRSA, VRE, or C. difficile. Acquisition of MRSA was not observed. Acquisition of VRE was documented.
CONCLUSION: This study documented that cooperative care was associated with some risk of healthcare-associated infection, most notably intravascular catheter-associated bloodstream infection and C. difficile-associated diarrhea, it appears the incidences of these infections were roughly commensurate with those in other care settings.

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Year:  2008        PMID: 18419364     DOI: 10.1086/587188

Source DB:  PubMed          Journal:  Infect Control Hosp Epidemiol        ISSN: 0899-823X            Impact factor:   3.254


  2 in total

1.  Evaluation of routine pretransplantation screening for methicillin-resistant Staphylococcus aureus in hematopoietic cell transplant recipients.

Authors:  Arianna Miles-Jay; Sara Podczervinski; Zach J Stednick; Steven A Pergam
Journal:  Am J Infect Control       Date:  2015-01       Impact factor: 2.918

2.  Outcomes of therapy: vancomycin-resistant enterococcal bacteremia in hematology and bone marrow transplant patients.

Authors:  Shawna Kraft; Emily Mackler; Peter Schlickman; Kathy Welch; Daryl D DePestel
Journal:  Support Care Cancer       Date:  2010-11-26       Impact factor: 3.603

  2 in total

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