Literature DB >> 18419343

Common nonsynonymous polymorphisms in the NOD2 gene are associated with resistance or susceptibility to tuberculosis disease in African Americans.

Celest M Austin1, Xin Ma, Edward A Graviss.   

Abstract

Pattern-recognition receptors (PRRs) play a key role in innate immunity against intracellular bacteria. NOD2 is one of the PRRs that contribute to the immune response to Mycobacterium tuberculosis infection. We sequenced coding regions of the NOD2 gene in 377 African Americans with tuberculosis (TB) disease and 187 ethnically matched control subjects. Three common nonsynonymous single-nucleotide polymorphisms--Pro268Ser, Arg702Trp, and Ala725Gly--demonstrated significant associations with TB disease. This finding may contribute to the future development of immunotherapy and immunoprophylaxis for TB disease.

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Year:  2008        PMID： 18419343     DOI： 10.1086/588384

Source DB:  PubMed          Journal:  J Infect Dis        ISSN： 0022-1899            Impact factor:   5.226


  46 in total

Review 1.  IL-17 and Th17 cells in tuberculosis.

Authors:  Egídio Torrado; Andrea M Cooper
Journal:  Cytokine Growth Factor Rev       Date:  2010-11-12       Impact factor: 7.638

Review 2.  Unleashing the therapeutic potential of NOD-like receptors.

Authors:  Kaoru Geddes; João G Magalhães; Stephen E Girardin
Journal:  Nat Rev Drug Discov       Date:  2009-06       Impact factor: 84.694

3.  NOD2 controls the nature of the inflammatory response and subsequent fate of Mycobacterium tuberculosis and M. bovis BCG in human macrophages.

Authors:  Michelle N Brooks; Murugesan V S Rajaram; Abul K Azad; Amal O Amer; Martin A Valdivia-Arenas; Jong-Hwan Park; Gabriel Núñez; Larry S Schlesinger
Journal:  Cell Microbiol       Date:  2010-11-24       Impact factor: 3.715

4.  Common polymorphisms in the NOD2 gene region are associated with leprosy and its reactive states.

Authors:  William Richard Berrington; Murdo Macdonald; Saraswoti Khadge; Bishwa Raj Sapkota; Marta Janer; Deanna Alisa Hagge; Gilla Kaplan; Thomas Richard Hawn
Journal:  J Infect Dis       Date:  2010-05-01       Impact factor: 5.226

5.  The novel human MRC1 gene polymorphisms are associated with susceptibility to pulmonary tuberculosis in Chinese Uygur and Kazak populations.

Authors:  Xing Zhang; Xiang Li; Wanjiang Zhang; Liliang Wei; Tingting Jiang; Zhongliang Chen; Chunping Meng; Jiyan Liu; Fang Wu; Chong Wang; Fujian Li; Xiaojun Sun; Zhongjie Li; Ji-Cheng Li
Journal:  Mol Biol Rep       Date:  2013-05-08       Impact factor: 2.316

Review 6.  Early clearance of Mycobacterium tuberculosis: a new frontier in prevention.

Authors:  Ayesha J Verrall; Mihai G Netea; Bachti Alisjahbana; Philip C Hill; Reimout van Crevel
Journal:  Immunology       Date:  2014-04       Impact factor: 7.397

Review 7.  C-type lectins with a sweet spot for Mycobacterium tuberculosis.

Authors:  G Lugo-Villarino; D Hudrisier; A Tanne; O Neyrolles
Journal:  Eur J Microbiol Immunol (Bp)       Date:  2011-03

Review 8.  Lung epithelial cells: therapeutically inducible effectors of antimicrobial defense.

Authors:  M M Leiva-Juárez; J K Kolls; S E Evans
Journal:  Mucosal Immunol       Date:  2017-08-16       Impact factor: 7.313

Review 9.  Immunometabolism within the tuberculosis granuloma: amino acids, hypoxia, and cellular respiration.

Authors:  Joseph E Qualls; Peter J Murray
Journal:  Semin Immunopathol       Date:  2015-10-21       Impact factor: 9.623

10.  Direct bacterial killing in vitro by recombinant Nod2 is compromised by Crohn's disease-associated mutations.

Authors:  Laurent-Herve Perez; Matt Butler; Tammy Creasey; JoAnn Dzink-Fox; John Gounarides; Stephanie Petit; Anna Ropenga; Neil Ryder; Kathryn Smith; Philip Smith; Scott J Parkinson
Journal:  PLoS One       Date:  2010-06-01       Impact factor: 3.240
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