Literature DB >> 18418085

ZAP-mediated mRNA degradation.

Yiping Zhu1, Guangxia Gao.   

Abstract

The zinc-finger antiviral protein (ZAP) is a host factor that inhibits the replication of many viruses by preventing the accumulation of viral mRNAs in the cytoplasm. ZAP specifically binds to the viral mRNA and recruits the cellular RNA degradation machinery to degrade the target RNA. In this article, we will review the work to date in understanding the mechanisms by which ZAP promotes viral mRNA decay and discuss future research directions to further investigate the function and underlying mechanisms of ZAP.

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Year:  2008        PMID： 18418085     DOI： 10.4161/rna.5.2.6044

Source DB:  PubMed          Journal:  RNA Biol        ISSN： 1547-6286            Impact factor:   4.652


  35 in total

1.  Structure of N-terminal domain of ZAP indicates how a zinc-finger protein recognizes complex RNA.

Authors:  Shoudeng Chen; Yihui Xu; Kuo Zhang; Xinlu Wang; Jian Sun; Guangxia Gao; Yingfang Liu
Journal:  Nat Struct Mol Biol       Date:  2012-03-11       Impact factor: 15.369

2.  New PARP gene with an anti-alphavirus function.

Authors:  Svetlana Atasheva; Maryna Akhrymuk; Elena I Frolova; Ilya Frolov
Journal:  J Virol       Date:  2012-05-23       Impact factor: 5.103

Review 3.  Interferon-Stimulated Genes as Enhancers of Antiviral Innate Immune Signaling.

Authors:  Keaton M Crosse; Ebony A Monson; Michael R Beard; Karla J Helbig
Journal:  J Innate Immun       Date:  2017-11-30       Impact factor: 7.349

4.  Structural basis for lack of ADP-ribosyltransferase activity in poly(ADP-ribose) polymerase-13/zinc finger antiviral protein.

Authors:  Tobias Karlberg; Mirjam Klepsch; Ann-Gerd Thorsell; C David Andersson; Anna Linusson; Herwig Schüler
Journal:  J Biol Chem       Date:  2015-01-29       Impact factor: 5.157

5.  Translational repression precedes and is required for ZAP-mediated mRNA decay.

Authors:  Yiping Zhu; Xinlu Wang; Stephen P Goff; Guangxia Gao
Journal:  EMBO J       Date:  2012-09-28       Impact factor: 11.598

6.  ZAP inhibits murine gammaherpesvirus 68 ORF64 expression and is antagonized by RTA.

Authors:  Yifang Xuan; Danyang Gong; Jing Qi; Chuanhui Han; Hongyu Deng; Guangxia Gao
Journal:  J Virol       Date:  2012-12-19       Impact factor: 5.103

7.  DEXH-Box protein DHX30 is required for optimal function of the zinc-finger antiviral protein.

Authors:  Peiying Ye; Shufeng Liu; Yiping Zhu; Guifang Chen; Guangxia Gao
Journal:  Protein Cell       Date:  2010-11-09       Impact factor: 14.870

8.  Zinc-finger antiviral protein inhibits HIV-1 infection by selectively targeting multiply spliced viral mRNAs for degradation.

Authors:  Yiping Zhu; Guifang Chen; Fengxiang Lv; Xinlu Wang; Xin Ji; Yihui Xu; Jing Sun; Li Wu; Yong-Tang Zheng; Guangxia Gao
Journal:  Proc Natl Acad Sci U S A       Date:  2011-08-29       Impact factor: 11.205

9.  Sindbis Virus Can Exploit a Host Antiviral Protein To Evade Immune Surveillance.

Authors:  Xinlu Wang; Melody M H Li; Jing Zhao; Shenglan Li; Margaret R MacDonald; Charles M Rice; Xiang Gao; Guangxia Gao
Journal:  J Virol       Date:  2016-10-28       Impact factor: 5.103

10.  Evolutionary history of the poly(ADP-ribose) polymerase gene family in eukaryotes.

Authors:  Matteo Citarelli; Sachin Teotia; Rebecca S Lamb
Journal:  BMC Evol Biol       Date:  2010-10-13       Impact factor: 3.260
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