Literature DB >> 1841686

Photo-CIDNP study of the interaction between the glucocorticoid receptor DNA-binding domain and glucocorticoid response elements.

E Kellenbach1, T Härd, R Boelens, K Dahlman, J Carlstedt-Duke, J A Gustafsson, G A van der Marel, J H van Boom, B Maler, K R Yamamoto.   

Abstract

Photo-CIDNP studies were performed on two protein fragments that both contain the double zinc-finger DNA-binding domain of the glucocorticoid receptor. In the absence of DNA, Tyr452 and Tyr474 are polarised in both fragments while Tyr497 is not. Addition of a palindromic glucocorticoid response element (GRE) results in the suppression of Tyr474 polarization while the polarization of Tyr452 is unaffected. The same result is observed upon adding a half GRE to the protein fragment indicating that the suppression of Tyr474 polarization is not due to protein-protein contacts but to interaction with DNA.

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Year:  1991        PMID： 1841686     DOI： 10.1007/bf01874574

Source DB:  PubMed          Journal:  J Biomol NMR        ISSN： 0925-2738            Impact factor:   2.835


  23 in total

1.  High level expression in Escherichia coli of the DNA-binding domain of the glucocorticoid receptor in a functional form utilizing domain-specific cleavage of a fusion protein.

Authors:  K Dahlman; P E Strömstedt; C Rae; H Jörnvall; J I Flock; J Carlstedt-Duke; J A Gustafsson
Journal:  J Biol Chem       Date:  1989-01-15       Impact factor: 5.157

2.  Protein-protein interactions facilitate DNA binding by the glucocorticoid receptor DNA-binding domain.

Authors:  K Dahlman-Wright; H Siltala-Roos; J Carlstedt-Duke; J A Gustafsson
Journal:  J Biol Chem       Date:  1990-08-15       Impact factor: 5.157

3.  Molecular interactions of steroid hormone receptor with its enhancer element: evidence for receptor dimer formation.

Authors:  S Y Tsai; J Carlstedt-Duke; N L Weigel; K Dahlman; J A Gustafsson; M J Tsai; B W O'Malley
Journal:  Cell       Date:  1988-10-21       Impact factor: 41.582

4.  Complex of lac repressor headpiece with a 14 base-pair lac operator fragment studied by two-dimensional nuclear magnetic resonance.

Authors:  R Boelens; R M Scheek; J H van Boom; R Kaptein
Journal:  J Mol Biol       Date:  1987-01-05       Impact factor: 5.469

Review 5.  Zinc fingers: gilt by association.

Authors:  R M Evans; S M Hollenberg
Journal:  Cell       Date:  1988-01-15       Impact factor: 41.582

6.  Laser photo-CIDNP detection of surface aromatic residues in dissociating bovine alpha-lactalbumin at submillimolar concentrations.

Authors:  L J Berliner; R Kaptein
Journal:  J Biol Chem       Date:  1980-04-25       Impact factor: 5.157

7.  The function and structure of the metal coordination sites within the glucocorticoid receptor DNA binding domain.

Authors:  L P Freedman; B F Luisi; Z R Korszun; R Basavappa; P B Sigler; K R Yamamoto
Journal:  Nature       Date:  1988-08-11       Impact factor: 49.962

8.  Mutations in the glucocorticoid receptor zinc finger region that distinguish interdigitated DNA binding and transcriptional enhancement activities.

Authors:  M Schena; L P Freedman; K R Yamamoto
Journal:  Genes Dev       Date:  1989-10       Impact factor: 11.361

9.  Photochemically induced dynamic nuclear polarization investigation of complex formation of the NH2-terminal DNA-binding domain of lac repressor with poly[d(AT)].

Authors:  F Buck; H Rüterjans; R Kaptein; K Beyreuther
Journal:  Proc Natl Acad Sci U S A       Date:  1980-09       Impact factor: 11.205

Review 10.  The steroid and thyroid hormone receptor superfamily.

Authors:  R M Evans
Journal:  Science       Date:  1988-05-13       Impact factor: 47.728
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  2 in total

1.  Comparison between intact and desialylated human serum amyloid P component by laser photo CIDNP (chemically induced dynamic nuclear polarization) technique: an indication for a conformational impact of sialic acid.

Authors:  H C Siebert; S André; G Reuter; R Kaptein; J F Vliegenthart; H J Gabius
Journal:  Glycoconj J       Date:  1997-12       Impact factor: 2.916

2.  Synthesis of isotope labeled oligonucleotides and their use in an NMR study of a protein-DNA complex.

Authors:  E R Kellenbach; M L Remerowski; D Eib; R Boelens; G A van der Marel; H van den Elst; J H van Boom; R Kaptein
Journal:  Nucleic Acids Res       Date:  1992-02-25       Impact factor: 16.971
  2 in total

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