| Literature DB >> 18416575 |
Mitchell Vamos1, Yoshihisa Kobayashi.
Abstract
The efficient, scalable preparation of both enantiomers of 2-(1-hydroxy-2-oxocyclohexyl)acetic acid in enantiomerically pure form is reported using environmentally benign conditions in 30% overall yield (6 steps) for the (S)-isomer, in 27% (7 steps) for the (R)-isomer, from cyclohexanone.Entities:
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Year: 2008 PMID： 18416575 DOI： 10.1021/jo8000904
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354