Literature DB >> 1841630

Venezuelan equine encephalitis virus propagation in the olfactory tract of normal and immunized mice.

A B Ryzhikov1, N V Tkacheva, A N Sergeev, E I Ryabchikova.   

Abstract

The role of virus spread in the induction of damage to the central nervous system (CNS) of mice infected with Venezuelan equine encephalitis virus (VEEV) via the respiratory route was studied. The virus concentration in various organs and in the blood, the sensitivity to different doses of virus, and ultrastructural lesions in various tissues were examined. It is concluded that VEEV can enter the CNS of nonimmunized mice both by vascular and by olfactory pathways, whereas in immunized mice the olfactory pathway is the main route.

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Year:  1991        PMID: 1841630

Source DB:  PubMed          Journal:  Biomed Sci


  14 in total

1.  Immunopathogenesis of alphaviruses.

Authors:  Victoria K Baxter; Mark T Heise
Journal:  Adv Virus Res       Date:  2020-07-08       Impact factor: 9.937

2.  Replication and clearance of Venezuelan equine encephalitis virus from the brains of animals vaccinated with chimeric SIN/VEE viruses.

Authors:  Slobodan Paessler; Haolin Ni; Olga Petrakova; Rafik Z Fayzulin; Nadezhda Yun; Michael Anishchenko; Scott C Weaver; Ilya Frolov
Journal:  J Virol       Date:  2006-03       Impact factor: 5.103

3.  Pegylated alpha interferon is an effective treatment for virulent venezuelan equine encephalitis virus and has profound effects on the host immune response to infection.

Authors:  R A Lukaszewski; T J Brooks
Journal:  J Virol       Date:  2000-06       Impact factor: 5.103

4.  Comparison of Aerosol- and Percutaneous-acquired Venezuelan Equine Encephalitis in Humans and Nonhuman Primates for Suitability in Predicting Clinical Efficacy under the Animal Rule.

Authors:  Janice M Rusnak; Lesley C Dupuy; Nancy A Niemuth; Andrew M Glenn; Lucy A Ward
Journal:  Comp Med       Date:  2018-10-03       Impact factor: 0.982

5.  CD4+ T cells provide protection against acute lethal encephalitis caused by Venezuelan equine encephalitis virus.

Authors:  Nadezhda E Yun; Bi-Hung Peng; Andrea S Bertke; Viktoriya Borisevich; Jennifer K Smith; Jeanon N Smith; Allison L Poussard; Milagros Salazar; Barbara M Judy; Michele A Zacks; D Mark Estes; Slobodan Paessler
Journal:  Vaccine       Date:  2009-05-03       Impact factor: 3.641

6.  Innate immune protection against infectious diseases by pulmonary administration of a phospholipid-conjugated TLR7 ligand.

Authors:  Christina C N Wu; Brian Crain; Shiyin Yao; Mojgan Sabet; Fitzgerald S Lao; Rommel I Tawatao; Michael Chan; Donald F Smee; Justin G Julander; Howard B Cottam; Donald G Guiney; Maripat Corr; Dennis A Carson; Tomoko Hayashi
Journal:  J Innate Immun       Date:  2013-11-01       Impact factor: 7.349

7.  Kinetic, Mutational, and Structural Studies of the Venezuelan Equine Encephalitis Virus Nonstructural Protein 2 Cysteine Protease.

Authors:  Xin Hu; Jaimee R Compton; Dagmar H Leary; Mark A Olson; Michael S Lee; Jonah Cheung; Wenjuan Ye; Mark Ferrer; Noel Southall; Ajit Jadhav; Elaine M Morazzani; Pamela J Glass; Juan Marugan; Patricia M Legler
Journal:  Biochemistry       Date:  2016-05-19       Impact factor: 3.162

8.  Differential host gene responses from infection with neurovirulent and partially-neurovirulent strains of Venezuelan equine encephalitis virus.

Authors:  Paridhi Gupta; Anuj Sharma; Jing Han; Amy Yang; Manish Bhomia; Barbara Knollmann-Ritschel; Raj K Puri; Radha K Maheshwari
Journal:  BMC Infect Dis       Date:  2017-04-26       Impact factor: 3.090

9.  Bioluminescent imaging and histopathologic characterization of WEEV neuroinvasion in outbred CD-1 mice.

Authors:  Aaron T Phillips; Charles B Stauft; Tawfik A Aboellail; Ann M Toth; Donald L Jarvis; Ann M Powers; Ken E Olson
Journal:  PLoS One       Date:  2013-01-02       Impact factor: 3.240

10.  Alpha-beta T cells provide protection against lethal encephalitis in the murine model of VEEV infection.

Authors:  Slobodan Paessler; Nadezhda E Yun; Barbara M Judy; Natallia Dziuba; Michele A Zacks; Anna H Grund; Ilya Frolov; Gerald A Campbell; Scott C Weaver; D Mark Estes
Journal:  Virology       Date:  2007-07-05       Impact factor: 3.616

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