Literature DB >> 18415881

Pediatric obesity: parallels with addiction and treatment recommendations.

Michelle C Acosta1, Jeanne Manubay, Frances R Levin.   

Abstract

Rates of pediatric obesity have increased dramatically over the past decade. This trend is especially alarming because obesity is associated with significant medical and psychosocial consequences. It may contribute to cardiovascular, metabolic, and hepatic complications, as well as to psychiatric difficulties. The development of obesity appears to be influenced by a complex array of genetic, metabolic, and neural frameworks, along with behavior, eating habits, and physical activity. Numerous parallels exist between obesity and addictive behaviors, including genetic predisposition, personality, environmental risk factors, and common neurobiological pathways in the brain. Typical treatments for pediatric obesity include behavioral interventions targeting diet or exercise. These treatments have yielded mixed results and typically have been examined in specialty clinic populations, limiting their generalizability. There are limited medication options for overweight children and adolescents, and no approved medical intervention in children younger than 16 years old. Bariatric surgery may be an option for some adolescents, but due to the risks of surgery, it is often seen as a last resort. The parallels between addiction and obesity aid in developing novel interventions for pediatric obesity. Motivational enhancement and cognitive-behavioral strategies used in addiction treatment may prove to be beneficial.

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Year:  2008        PMID: 18415881      PMCID: PMC3352597          DOI: 10.1080/10673220802069764

Source DB:  PubMed          Journal:  Harv Rev Psychiatry        ISSN: 1067-3229            Impact factor:   3.732


  229 in total

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Review 3.  A neural substrate of prediction and reward.

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Journal:  Lancet       Date:  2005 Apr 16-22       Impact factor: 79.321

5.  Effect of sibutramine on weight maintenance after weight loss: a randomised trial. STORM Study Group. Sibutramine Trial of Obesity Reduction and Maintenance.

Authors:  W P James; A Astrup; N Finer; J Hilsted; P Kopelman; S Rössner; W H Saris; L F Van Gaal
Journal:  Lancet       Date:  2000 Dec 23-30       Impact factor: 79.321

6.  Sibutramine as an adjuvant therapy in adolescents suffering from morbid obesity.

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Journal:  Isr Med Assoc J       Date:  2006-01       Impact factor: 0.892

7.  Flutamide-metformin therapy to reduce fat mass in hyperinsulinemic ovarian hyperandrogenism: effects in adolescents and in women on third-generation oral contraception.

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8.  The relationship of body mass index and blood pressure in primary care pediatric patients.

Authors:  Bonita Falkner; Samuel S Gidding; Gabriela Ramirez-Garnica; Stacey Armatti Wiltrout; David West; Elizabeth B Rappaport
Journal:  J Pediatr       Date:  2006-02       Impact factor: 4.406

9.  Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2-arachidonoyl glycerol.

Authors:  Tim C Kirkham; Claire M Williams; Filomena Fezza; Vincenzo Di Marzo
Journal:  Br J Pharmacol       Date:  2002-06       Impact factor: 8.739

10.  Elevated fasting plasma ghrelin in prader-willi syndrome adults is not solely explained by their reduced visceral adiposity and insulin resistance.

Authors:  Anthony P Goldstone; E Louise Thomas; Audrey E Brynes; Gabriela Castroman; Ray Edwards; Mohammad A Ghatei; Gary Frost; Anthony J Holland; Ashley B Grossman; Márta Korbonits; Stephen R Bloom; Jimmy D Bell
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  8 in total

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Review 2.  Circuits controlling energy balance and mood: inherently intertwined or just complicated intersections?

Authors:  Chen Liu; Syann Lee; Joel K Elmquist
Journal:  Cell Metab       Date:  2014-03-13       Impact factor: 27.287

Review 3.  The relationship between opioid and sugar intake: review of evidence and clinical applications.

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Journal:  J Opioid Manag       Date:  2010 Nov-Dec

Review 4.  A systematic review of pediatric obesity and family communication through the lens of addiction literature.

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Journal:  Child Obes       Date:  2014-05-08       Impact factor: 2.992

5.  Neuro-Genetics of Reward Deficiency Syndrome (RDS) as the Root Cause of "Addiction Transfer": A New Phenomenon Common after Bariatric Surgery.

Authors:  Kenneth Blum; John Bailey; Anthony M Gonzalez; Marlene Oscar-Berman; Yijun Liu; John Giordano; Eric Braverman; Mark Gold
Journal:  J Genet Syndr Gene Ther       Date:  2011-12-23

6.  Obesity and substance misuse: is there a relationship?

Authors:  Randy A Sansone; Lori A Sansone
Journal:  Innov Clin Neurosci       Date:  2013-09

7.  Executive Function Training in Childhood Obesity: Food Choice, Quality of Life, and Brain Connectivity (TOuCH): A Randomized Control Trial Protocol.

Authors:  Cristina Sanchez-Castañeda; Sandra Luis-Ruiz; Marta Ramon-Krauel; Carles Lerin; Consuelo Sanchez; Núria Miró; Sònia Martínez; Maite Garolera; Maria Angeles Jurado
Journal:  Front Pediatr       Date:  2021-02-24       Impact factor: 3.418

8.  Description of the EUROBIS program: a combination of an Epode community-based and a clinical care intervention to improve the lifestyles of children and adolescents with overweight or obesity.

Authors:  Claudia Mazzeschi; Chiara Pazzagli; Loredana Laghezza; Dalila Battistini; Elisa Reginato; Chiara Perrone; Claudia Ranucci; Cristina Fatone; Roberto Pippi; Maria Donata Giaimo; Alberto Verrotti; Giovanni De Giorgi; Pierpaolo De Feo
Journal:  Biomed Res Int       Date:  2014-08-04       Impact factor: 3.411

  8 in total

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