Literature DB >> 18414436

Role for alkaline phosphatase as an inducer of vascular calcification in renal failure?

M Schoppet1, C M Shanahan.   

Abstract

Vascular calcification is associated with increased cardiovascular morbidity and mortality. A number of calcification inhibitors have been defined recently, including inorganic pyrophosphate (PP(i)), an important physicochemical inhibitor of hydroxyapatite crystal growth. Increased hydrolysis of PP(i) by tissue-nonspecific alkaline phosphatase (TNAP) may occur in renal failure and act to enhance mineralization of vessels.

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Year:  2008        PMID: 18414436     DOI: 10.1038/ki.2008.104

Source DB:  PubMed          Journal:  Kidney Int        ISSN: 0085-2538            Impact factor:   10.612


  55 in total

1.  Predictors of sudden cardiac death: a competing risk approach in the hemodialysis study.

Authors:  Shani Shastri; Navdeep Tangri; Hocine Tighiouart; Gerald J Beck; Panagiotis Vlagopoulos; Daniel Ornt; Garabed Eknoyan; John W Kusek; Charles Herzog; Alfred K Cheung; Mark J Sarnak
Journal:  Clin J Am Soc Nephrol       Date:  2011-11-10       Impact factor: 8.237

Review 2.  Kidney bone disease and mortality in CKD: revisiting the role of vitamin D, calcimimetics, alkaline phosphatase, and minerals.

Authors:  Kamyar Kalantar-Zadeh; Anuja Shah; Uyen Duong; Rulin C Hechter; Ramanath Dukkipati; Csaba P Kovesdy
Journal:  Kidney Int Suppl       Date:  2010-08       Impact factor: 10.545

3.  Histomorphometric diagnostics of renal osteopathy in chronic dialysis patients at high risk of cardiovascular disease.

Authors:  K Žamboch; K Krejčí; J Škarda; M Tichý; I Überall; P Skýpalová; K Langová; D Stejskal; M Švesták; J Zahálková; V Ščudla; J Zadražil
Journal:  Int Urol Nephrol       Date:  2015-05-01       Impact factor: 2.370

4.  Outcome predictability of serum alkaline phosphatase in men with pre-dialysis CKD.

Authors:  Csaba P Kovesdy; Vitalie Ureche; Jun L Lu; Kamyar Kalantar-Zadeh
Journal:  Nephrol Dial Transplant       Date:  2010-03-17       Impact factor: 5.992

5.  Alkaline phosphatase and mortality in patients on peritoneal dialysis.

Authors:  Xinhui Liu; Qunying Guo; Xiaoran Feng; Juan Wang; Juan Wu; Haiping Mao; Fengxian Huang; Xueqing Yu; Xiao Yang
Journal:  Clin J Am Soc Nephrol       Date:  2014-01-23       Impact factor: 8.237

6.  Association of serum alkaline phosphatase and bone mineral density in maintenance hemodialysis patients.

Authors:  Jong Chan Park; Csaba P Kovesdy; Uyen Duong; Elani Streja; Mehdi Rambod; Allen R Nissenson; Stuart M Sprague; Kamyar Kalantar-Zadeh
Journal:  Hemodial Int       Date:  2010-03-24       Impact factor: 1.812

7.  Serum sclerostin: the missing link in the bone-vessel cross-talk in hemodialysis patients?

Authors:  S Pelletier; C B Confavreux; J Haesebaert; F Guebre-Egziabher; J Bacchetta; M-C Carlier; L Chardon; M Laville; R Chapurlat; G M London; M-H Lafage-Proust; D Fouque
Journal:  Osteoporos Int       Date:  2015-04-25       Impact factor: 4.507

8.  Serum alkaline phosphatase predicts mortality among maintenance hemodialysis patients.

Authors:  Deborah L Regidor; Csaba P Kovesdy; Rajnish Mehrotra; Mehdi Rambod; Jennie Jing; Charles J McAllister; David Van Wyck; Joel D Kopple; Kamyar Kalantar-Zadeh
Journal:  J Am Soc Nephrol       Date:  2008-07-30       Impact factor: 10.121

9.  Chronic mineral dysregulation promotes vascular smooth muscle cell adaptation and extracellular matrix calcification.

Authors:  Rukshana C Shroff; Rosamund McNair; Jeremy N Skepper; Nichola Figg; Leon J Schurgers; John Deanfield; Lesley Rees; Catherine M Shanahan
Journal:  J Am Soc Nephrol       Date:  2009-12-03       Impact factor: 10.121

10.  Systemic injection of planktonic forms of mammalian-derived nanoparticles alters arterial response to injury in rabbits.

Authors:  Maria K Schwartz; John C Lieske; Larry W Hunter; Virginia M Miller
Journal:  Am J Physiol Heart Circ Physiol       Date:  2009-03-13       Impact factor: 4.733

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