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Literature DB >> 18413847

Biomarkers in early clinical trials: the committed and the skeptics.

Udai Banerji, Johann de Bono, Ian Judson, Stanley Kaye, Paul Workman.

Abstract

Mesh：

Substances：
Biomarkers, Tumor

Year: 2008 PMID： 18413847 DOI： 10.1158/1078-0432.CCR-07-5224

Source DB: PubMed Journal: Clin Cancer Res ISSN： 1078-0432 Impact factor: 12.531

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Cited

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17 in total

1. Mechanistic evaluation of the novel HSP90 inhibitor NVP-AUY922 in adult and pediatric glioblastoma.

Authors: Nathalie Gaspar; Swee Y Sharp; Suzanne A Eccles; Sharon Gowan; Sergey Popov; Chris Jones; Andrew Pearson; Gilles Vassal; Paul Workman
Journal: Mol Cancer Ther Date: 2010-05 Impact factor: 6.261

Review 2. Envisioning the future of early anticancer drug development.

Authors: Timothy A Yap; Shahneen K Sandhu; Paul Workman; Johann S de Bono
Journal: Nat Rev Cancer Date: 2010-06-10 Impact factor: 60.716

3. Underreporting of Research Biopsies from Clinical Trials in Oncology.

Authors: Christine M Parseghian; Kanwal Raghav; Robert A Wolff; Joe Ensor; James Yao; Lee M Ellis; Alda L Tam; Michael J Overman
Journal: Clin Cancer Res Date: 2017-07-28 Impact factor: 12.531

4. A novel HSP90 inhibitor delays castrate-resistant prostate cancer without altering serum PSA levels and inhibits osteoclastogenesis.

Authors: Francois Lamoureux; Christian Thomas; Min-Jean Yin; Hidetoshi Kuruma; Ladan Fazli; Martin E Gleave; Amina Zoubeidi
Journal: Clin Cancer Res Date: 2011-02-24 Impact factor: 12.531

5. Histone deacetylase inhibition increases levels of choline kinase α and phosphocholine facilitating noninvasive imaging in human cancers.

Authors: Mounia Beloueche-Babari; Vaitha Arunan; Helen Troy; Robert H te Poele; Anne-Christine Wong te Fong; L Elizabeth Jackson; Geoffrey S Payne; John R Griffiths; Ian R Judson; Paul Workman; Martin O Leach; Yuen-Li Chung
Journal: Cancer Res Date: 2011-12-22 Impact factor: 12.701

6. Ethics of mandatory research biopsy for correlative end points within clinical trials in oncology.

Authors: Jeffrey Peppercorn; Iuliana Shapira; Deborah Collyar; Teresa Deshields; Nancy Lin; Ian Krop; Hans Grunwald; Paula Friedman; Ann H Partridge; Richard L Schilsky; Monica M Bertagnolli
Journal: J Clin Oncol Date: 2010-04-20 Impact factor: 44.544

Biomarkers in early clinical trials: the committed and the skeptics.

1. Mechanistic evaluation of the novel HSP90 inhibitor NVP-AUY922 in adult and pediatric glioblastoma.

Review 2. Envisioning the future of early anticancer drug development.

3. Underreporting of Research Biopsies from Clinical Trials in Oncology.

4. A novel HSP90 inhibitor delays castrate-resistant prostate cancer without altering serum PSA levels and inhibits osteoclastogenesis.

5. Histone deacetylase inhibition increases levels of choline kinase α and phosphocholine facilitating noninvasive imaging in human cancers.

6. Ethics of mandatory research biopsy for correlative end points within clinical trials in oncology.

Review 7. Beyond chemotherapy: targeted therapies in ovarian cancer.

8. Use of research biopsies in clinical trials: are risks and benefits adequately discussed?

9. Clinical benefit in Phase-I trials of novel molecularly targeted agents: does dose matter?

Review 10. Metabolic assessment of the action of targeted cancer therapeutics using magnetic resonance spectroscopy.