Literature DB >> 18412810

Cutaneous chancroid in a visitor from Vanuatu.

William J H McBride1, Rory C S Hannah, Genevera M Le Cornec, Cheryl Bletchly.   

Abstract

A 23-year-old woman from Vanuatu presented to an Australian hospital with a 3-week history of a non-healing ulcer on the lower leg. A swab was submitted for a multiplex polymerase chain reaction designed to investigate genital ulcerative conditions. Haemophilus ducreyi was detected and the gene product was subsequently sequenced, confirming the diagnosis of cutaneous chancroid. The lesion responded to intramuscular benzathine penicillin. This report adds further evidence that cutaneous chancroid should be considered in the evaluation of skin ulcers in the south Pacific.

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Year:  2008        PMID: 18412810     DOI: 10.1111/j.1440-0960.2008.00439.x

Source DB:  PubMed          Journal:  Australas J Dermatol        ISSN: 0004-8380            Impact factor:   2.875


  23 in total

1.  Sialylation of lipooligosaccharides is dispensable for the virulence of Haemophilus ducreyi in humans.

Authors:  Stanley M Spinola; Wei Li; Kate R Fortney; Diane M Janowicz; Beth Zwickl; Barry P Katz; Robert S Munson
Journal:  Infect Immun       Date:  2011-12-05       Impact factor: 3.441

Review 2.  The endemic treponematoses.

Authors:  Lorenzo Giacani; Sheila A Lukehart
Journal:  Clin Microbiol Rev       Date:  2014-01       Impact factor: 26.132

3.  Haemophilus ducreyi infection induces activation of the NLRP3 inflammasome in nonpolarized but not in polarized human macrophages.

Authors:  Wei Li; Barry P Katz; Margaret E Bauer; Stanley M Spinola
Journal:  Infect Immun       Date:  2013-06-10       Impact factor: 3.441

4.  Putative vaccine candidates and drug targets identified by reverse vaccinology and subtractive genomics approaches to control Haemophilus ducreyi, the causative agent of chancroid.

Authors:  Alissa de Sarom; Arun Kumar Jaiswal; Sandeep Tiwari; Letícia de Castro Oliveira; Debmalya Barh; Vasco Azevedo; Carlo Jose Oliveira; Siomar de Castro Soares
Journal:  J R Soc Interface       Date:  2018-05       Impact factor: 4.118

5.  Haemophilus ducreyi lipooligosaccharides induce expression of the immunosuppressive enzyme indoleamine 2,3-dioxygenase via type I interferons and tumor necrosis factor alpha in human dendritic cells.

Authors:  Wei Li; Barry P Katz; Stanley M Spinola
Journal:  Infect Immun       Date:  2011-05-16       Impact factor: 3.441

6.  Haemophilus ducreyi-induced interleukin-10 promotes a mixed M1 and M2 activation program in human macrophages.

Authors:  Wei Li; Barry P Katz; Stanley M Spinola
Journal:  Infect Immun       Date:  2012-10-01       Impact factor: 3.441

7.  Defining Potential Vaccine Targets of Haemophilus ducreyi Trimeric Autotransporter Adhesin DsrA.

Authors:  William G Fusco; Neelima R Choudhary; Shelley M Stewart; S Munir Alam; Gregory D Sempowski; Christopher Elkins; Isabelle Leduc
Journal:  Monoclon Antib Immunodiagn Immunother       Date:  2015-04

8.  Passive immunization with a polyclonal antiserum to the hemoglobin receptor of Haemophilus ducreyi confers protection against a homologous challenge in the experimental swine model of chancroid.

Authors:  Isabelle Leduc; William G Fusco; Neelima Choudhary; Patty A Routh; Deborah M Cholon; Marcia M Hobbs; Glen W Almond; Paul E Orndorff; Christopher Elkins
Journal:  Infect Immun       Date:  2011-06-06       Impact factor: 3.441

9.  Carbon storage regulator A contributes to the virulence of Haemophilus ducreyi in humans by multiple mechanisms.

Authors:  Dharanesh Gangaiah; Wei Li; Kate R Fortney; Diane M Janowicz; Sheila Ellinger; Beth Zwickl; Barry P Katz; Stanley M Spinola
Journal:  Infect Immun       Date:  2012-12-10       Impact factor: 3.441

10.  Experimental infection of human volunteers with Haemophilus ducreyi: fifteen years of clinical data and experience.

Authors:  Diane M Janowicz; Susan Ofner; Barry P Katz; Stanley M Spinola
Journal:  J Infect Dis       Date:  2009-06-01       Impact factor: 5.226

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