Literature DB >> 18411800

[Intramedullary spinal cord metastasis treated with radiation therapy: report of 3 cases].

Shogo Endo1, Kazutoshi Hida, Shunsuke Yano, Masaki Ito, Shigeru Yamaguchi, Daina Kashiwazaki, Rumiko Kinoshita, Hiroki Shirato, Yoshinobu Iwasaki.   

Abstract

OBJECTIVES: Intramedurally spinal cord metastasis (ISCM) tends to be seen in the end period of the malignant tumor, so it is important to choose a therapeutic method regarding the QOL (quality of life) of the patient. In this study, we reported three cases of ISCM treated by radiation therapy alone, and demonstrated the utility of this therapeutic procedure. PATIENTS AND METHODS: From 2005 to 2006, 3 cases of ISCM underwent radiotherapy in our institution. The mean age of the patients was 64.0 years old, and all patients were men, having lung carcinoma as their primary lesions. The lesions were located at the cervical cord in one case and the conus medullaris in the other two cases. They were treated by radiotherapy at the department of radiology in our institute.
RESULTS: The tumor size and intramedullary high signal area on MR images after the radiotherapy were reduced in all patients. During the clinical course, neurological symptoms were improved in two patients, and progression of the symptoms was stopped in one patient. All of the patients obtained a better ADL due to the radiotherapy.
CONCLUSIONS: Radiotherapy has an advantage over surgical treatment in that it involves less invasion. The treatment brought improvements of clinical symptoms and radiological findings in the patients with ISCM. So, radiotherapy could be used as one of the major treatments for patients with ISCM who desire a better QOL after treatment.

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Year:  2008        PMID: 18411800

Source DB:  PubMed          Journal:  No Shinkei Geka        ISSN: 0301-2603


  3 in total

1.  Stereotactic radiotherapy for spinal intradural metastases developing within or adjacent to the previous irradiation field--report of three cases.

Authors:  Yoshimasa Mori; Chisa Hashizume; Yuta Shibamoto; Tatsuya Kobayashi; Hisato Nakazawa; Masahiro Hagiwara; Takahiko Tsugawa
Journal:  Nagoya J Med Sci       Date:  2013-08       Impact factor: 1.131

2.  Stereotactic Radiotherapy for Cervical Spinal Intramedullary Metastasis and Multiple Brain Metastases: A Case Report.

Authors:  Yoshimasa Mori; Toshiki Kawamura; Yukihiko Ohshima; Arisa Takeuchi; Toshie Mori; Tuneo Ishiguchi
Journal:  Cureus       Date:  2016-04-27

3.  Intramedullary Metastasis to the Cervical Spinal Cord from Malignant Pleural Mesothelioma: Review of the Literature and Case Reports.

Authors:  Fotios Kalfas; Claudia Scudieri
Journal:  Asian J Neurosurg       Date:  2020-02-25
  3 in total

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