| Literature DB >> 18411181 |
Abstract
It is tempting to speculate that all diabetic complications are generated by a single biochemical abnormality. The observation that intracellular inositol depletion occurs in diabetes mellitus has led to the hypothesis that this may be of importance in the pathogenesis of diabetic complications. The central role of inositol and inositol derivatives in cellular function has given support to this theory, but as yet no fully substantiated mechanistic model can be offered.Entities:
Year: 1991 PMID： 18411181 DOI： 10.1016/1043-2760(91)90017-h
Source DB: PubMed Journal: Trends Endocrinol Metab ISSN： 1043-2760 Impact factor: 12.015