Literature DB >> 18410867

Preoperative beta-blocker use: impact of national guidelines on clinical practice.

Shamsuddin Akhtar1, Sheriff Assaad, Muzna Amin, Natalie F Holt, Paul G Barash, David G Silverman.   

Abstract

STUDY
OBJECTIVE: To determine if recommendations regarding perioperative beta-blocker therapy were followed by an increase in the number of eligible presurgical patients receiving beta-blockers and the number achieving the recommended heart rate (HR <60 beats per minute [bpm]).
DESIGN: Retrospective, observational study.
SETTING: Tertiary-care teaching hospital. MEASUREMENTS: The records of all 718 patients who underwent elective vascular surgery or coronary artery bypass grafting between January 2001 and March 2002 (pre-guideline) and those who did so between April 2002 and September 2003 (post-guideline) were reviewed. Percentage of eligible patients who received beta-blockers preoperatively and the target HR achieved in pre-guideline versus post-guideline patients were recorded. Differences were assessed using the unpaired t test and chi2 analysis. A P value of less than 0.05 is reported. MAIN
RESULTS: Fifty percent of the post-guideline patients in the vascular surgery group were receiving beta-blockers at the time of preanesthetic evaluation versus 48% of pre-guideline patients (P = nonsignificant [NS]). Mean HR in the vascular surgery post-guideline beta-blocker group (70 +/- 14 bpm) was higher than in the pre-guideline beta-blocker group (65 +/- 11 bpm) (P < 0.01). Only 22% of those vascular surgery patients in the post-guideline group who were taking beta-blockers achieved the target HR of less than 60 bpm versus 29% of the vascular surgery patients taking beta-blockers in the pre-guideline group (P = NS). In the coronary artery bypass grafting group, 80% of post-guideline patients received beta-blocker before anesthesia assessment versus 75% of pre-guideline patients (P = NS). Mean HR in the post-guideline beta-blocker group (67 +/- 15 bpm) was similar to the pre-guideline beta-blocker group (64 +/- 13 bpm) (P = NS). Only 28% of the post-guideline patients who were receiving beta-blockers achieved the target HR of less than 60 bpm, which was not significantly different from the 17% achieved in the pre-guideline group (P = NS).
CONCLUSION: At our institution, preoperative beta-blocker use was not significantly changed by publication of the recommendations.

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Year:  2008        PMID: 18410867     DOI: 10.1016/j.jclinane.2007.09.012

Source DB:  PubMed          Journal:  J Clin Anesth        ISSN: 0952-8180            Impact factor:   9.452


  2 in total

1.  β-blocker withdrawal among patients presenting for surgery from home.

Authors:  Robert B Schonberger; Carrie L Lukens; O Dicle Turkoglu; Jessica L Feinleib; Kenneth L Haspel; Matthew M Burg
Journal:  J Cardiothorac Vasc Anesth       Date:  2012-03-13       Impact factor: 2.628

Review 2.  Preoperative evaluation and a risk assessment in patients undergoing abdominal surgery.

Authors:  Siyamek Neragi-Miandoab; Michael Wayne; Michael Cioroiu; Lee M Zank; Christopher Mills
Journal:  Surg Today       Date:  2010-01-28       Impact factor: 2.549

  2 in total

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