Literature DB >> 18410764

Variation in inpatient resource utilization and management of apparent life-threatening events.

Joel S Tieder1, Charles A Cowan, Michelle M Garrison, Dimitri A Christakis.   

Abstract

OBJECTIVE: To report national variations in diagnostic approaches to apparent life-threatening events (ALTEs) and resource utilization. STUDY
DESIGN: Using the Pediatric Health Information System, we studied children who were age 3 days to 5 months at admission and were discharged with an International Classification of Diseases, Ninth Revision (ICD-9) code potentially identifiable as ALTE. Multiple analysis of variance was used to determine whether the variances in adjusted charges, length of stay (LOS), and diagnostic studies were hospital-related after controlling for other covariates. Logistic regression was used to study the association of readmission rates with discharge diagnosis and specific diagnostic studies.
RESULTS: The study group comprised 12,067 patients, with a mean LOS of 4.4 days (standard deviation +/- 5.6 days) and mean adjusted charges of $15,567 ($28,510) per admission. The mean in-hospital mortality rate was 0.56% (n = 68), and the rate of 30-day readmission was 2.5%. The most common discharge diagnoses were gastroesophageal reflux 36.9% (48.3%) and lower respiratory tract infection 30.8% (46.2%). Mean LOS, total adjusted charges, and use of diagnostic studies varied considerably across hospitals, and hospital-level differences were a significant contributor to the variance of these outcomes after controlling for covariates (P < .001). There was an increased likelihood of readmission for patients discharged with a diagnosis of cardiovascular disorders (odds ratio [OR] = 1.68; 95% confidence interval [CI] = 1.30 to 2.16) and gastroesophageal reflux (OR = 1.32; 95% CI = 1.03 to 1.69) compared with other discharge diagnoses.
CONCLUSIONS: There is considerable hospital-based variation in care for patients hospitalized for conditions potentially identifiable as ALTE, particularly in the evaluation and diagnosis of gastroesophageal reflux, which may contribute to adverse clinical and financial outcomes. An evidence-based national standard of care for ALTE is needed, as are multi-institutional initiatives to study different diagnostic and management strategies and their effect on patient outcomes.

Entities:  

Mesh:

Year:  2008        PMID: 18410764     DOI: 10.1016/j.jpeds.2007.11.024

Source DB:  PubMed          Journal:  J Pediatr        ISSN: 0022-3476            Impact factor:   4.406


  11 in total

1.  Respiratory events in infants presenting with apparent life threatening events: is there an explanation from esophageal motility?

Authors:  Kathryn A Hasenstab; Sudarshan R Jadcherla
Journal:  J Pediatr       Date:  2014-03-28       Impact factor: 4.406

2.  Oropharyngeal Dysphagia Is Strongly Correlated With Apparent Life-Threatening Events.

Authors:  Daniel R Duncan; Janine Amirault; Paul D Mitchell; Kara Larson; Rachel L Rosen
Journal:  J Pediatr Gastroenterol Nutr       Date:  2017-08       Impact factor: 2.839

3.  Accuracy of administrative billing codes to detect urinary tract infection hospitalizations.

Authors:  Joel S Tieder; Matthew Hall; Katherine A Auger; Paul D Hain; Karen E Jerardi; Angela L Myers; Suraiya S Rahman; Derek J Williams; Samir S Shah
Journal:  Pediatrics       Date:  2011-07-18       Impact factor: 7.124

4.  Herpes simplex virus testing and hospital length of stay in neonates and young infants.

Authors:  Samir S Shah; Jessica Volk; Zeinab Mohamad; Richard L Hodinka; Joseph J Zorc
Journal:  J Pediatr       Date:  2010-02-10       Impact factor: 4.406

5.  Hospital variation in nitric oxide use for premature infants.

Authors:  Michael R Stenger; Jonathan L Slaughter; Kelly Kelleher; Edward G Shepherd; Mark A Klebanoff; Patricia Reagan; Leif D Nelin; William Gardner
Journal:  Pediatrics       Date:  2012-03-12       Impact factor: 7.124

6.  Pharyngoesophageal and cardiorespiratory interactions: potential implications for premature infants at risk of clinically significant cardiorespiratory events.

Authors:  Kathryn A Hasenstab; Saira Nawaz; Ivan M Lang; Reza Shaker; Sudarshan R Jadcherla
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2018-12-13       Impact factor: 4.052

Review 7.  Home Cardiorespiratory Monitoring in Infants at Risk for Sudden Infant Death Syndrome (SIDS), Apparent Life-Threatening Event (ALTE) or Brief Resolved Unexplained Event (BRUE).

Authors:  Chiara Sodini; Letizia Paglialonga; Giulia Antoniol; Serafina Perrone; Nicola Principi; Susanna Esposito
Journal:  Life (Basel)       Date:  2022-06-13

Review 8.  Infantile Apparent Life-Threatening Events, an Educational Review.

Authors:  Hamed Aminiahidashti
Journal:  Emerg (Tehran)       Date:  2015

Review 9.  Apparent life-threatening event in infancy.

Authors:  Hee Joung Choi; Yeo Hyang Kim
Journal:  Korean J Pediatr       Date:  2016-09-21

Review 10.  Apparent Life-Threatening Events (ALTE): Italian guidelines.

Authors:  Raffaele Piumelli; Riccardo Davanzo; Niccolò Nassi; Silvia Salvatore; Cinzia Arzilli; Marta Peruzzi; Massimo Agosti; Antonella Palmieri; Maria Giovanna Paglietti; Luana Nosetti; Raffaele Pomo; Francesco De Luca; Alessandro Rimini; Salvatore De Masi; Simona Costabel; Valeria Cavarretta; Anna Cremante; Fabio Cardinale; Renato Cutrera
Journal:  Ital J Pediatr       Date:  2017-12-12       Impact factor: 2.638

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