Literature DB >> 18410456

Chronic lymphocytic leukaemia and acute myeloid leukaemia are not associated with AKT1 pleckstrin homology domain (E17K) mutations.

T Zenz, K Döhner, T Denzel, H Döhner, S Stilgenbauer, L Bullinger.   

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Year:  2008        PMID： 18410456     DOI： 10.1111/j.1365-2141.2008.07113.x

Source DB:  PubMed          Journal:  Br J Haematol        ISSN： 0007-1048            Impact factor:   6.998


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  7 in total

1.  Constitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice.

Authors:  Michael G Kharas; Rachel Okabe; Jared J Ganis; Maricel Gozo; Tulasi Khandan; Mahnaz Paktinat; D Gary Gilliland; Kira Gritsman
Journal:  Blood       Date:  2009-12-14       Impact factor: 22.113

2.  The oncogenic mutation in the pleckstrin homology domain of AKT1 in endometrial carcinomas.

Authors:  K Shoji; K Oda; S Nakagawa; S Hosokawa; G Nagae; Y Uehara; K Sone; Y Miyamoto; H Hiraike; O Hiraike-Wada; T Nei; K Kawana; H Kuramoto; H Aburatani; T Yano; Y Taketani
Journal:  Br J Cancer       Date:  2009-06-02       Impact factor: 7.640

Review 3.  Chronic lymphocytic leukemia: interplay between noncoding RNAs and protein-coding genes.

Authors:  George A Calin; Carlo M Croce
Journal:  Blood       Date:  2009-09-10       Impact factor: 22.113

4.  Cancer associated E17K mutation causes rapid conformational drift in AKT1 pleckstrin homology (PH) domain.

Authors:  Ambuj Kumar; Rituraj Purohit
Journal:  PLoS One       Date:  2013-05-31       Impact factor: 3.240

Review 5.  Prognostic impact of the MDM2SNP309 allele in leukemia and lymphoma.

Authors:  Sean M Post; Vinod Pant; Hussein Abbas; Alfonso Quintás-Cardama
Journal:  Oncotarget       Date:  2010-07

6.  Cell cycle-dependent activity of the novel dual PI3K-MTORC1/2 inhibitor NVP-BGT226 in acute leukemia.

Authors:  Kerstin Maria Kampa-Schittenhelm; Michael Charles Heinrich; Figen Akmut; Katharina Henriette Rasp; Barbara Illing; Hartmut Döhner; Konstanze Döhner; Marcus Matthias Schittenhelm
Journal:  Mol Cancer       Date:  2013-05-24       Impact factor: 27.401

7.  The transforming mutation E17K/AKT1 is not a major event in B-cell-derived lymphoid leukaemias.

Authors:  I S Mahmoud; M A Sughayer; H A Mohammad; A S Awidi; M S EL-Khateeb; S I Ismail
Journal:  Br J Cancer       Date:  2008-08-05       Impact factor: 7.640
  7 in total

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