Literature DB >> 18410335

Is there an easier way to autograft skin in chronic leg ulcers? 'Minced micrografts', a new technique.

P Boggio1, R Tiberio, M Gattoni, E Colombo, G Leigheb.   

Abstract

BACKGROUND: Chronic venous leg ulcers represent an urgent and increasing problem for public health. The use of skin autografts results in a greater therapeutic success in healing chronic ulcers.
OBJECTIVE: A simple method of skin autografting that could permit a wider use of skin grafts in outpatients is needed. A new technique allowing skin autografting in a simple one-step process, without complex surgical procedures or expensive technical supplies, is presented.
METHODS: A small, full-thickness skin specimen taken from the patient is finely minced and spread on his leg ulcer bed allowing to cover a surface many times wider than the sample itself.
RESULTS: This method induces faster re-epithelization of chronic leg ulcers that failed to heal despite good conservative local therapy and give the possibility to repair very large ulcers with small fragments of skin. A clinical case is shown as an example out of 20 ulcers we recently treated.
CONCLUSION: Our preliminary report shows that this technique results in a greater therapeutic success (18 of 20 cases) in healing chronic leg ulcers, a common pathology that often affects outpatients treated for very long periods at home or in the Dermatologist's office. In our experience, this new and successful reparative possibility makes 'mince grafting' a recommendable procedure.

Entities:  

Mesh:

Year:  2008        PMID: 18410335     DOI: 10.1111/j.1468-3083.2008.02737.x

Source DB:  PubMed          Journal:  J Eur Acad Dermatol Venereol        ISSN: 0926-9959            Impact factor:   6.166


  6 in total

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Authors:  Ming Chen; Melissa Przyborowski; Francois Berthiaume
Journal:  Crit Rev Biomed Eng       Date:  2009

2.  Treatment of Deliberate Self-harm Scars with Rotated Thin-skin Graft and Minced-skin Graft.

Authors:  Kento Takaya; Ruka Hayashi; Noriko Aramaki-Hattori; Keisuke Okabe; Shigeki Sakai; Toru Asou; Kazuo Kishi
Journal:  Plast Reconstr Surg Glob Open       Date:  2020-08-19

3.  Fate of the dermal component of micrografts in full-thickness wounds.

Authors:  Mansher Singh; Kristo Nuutila; Carla Kruse; Edward J Caterson; Scott R Granter; Elof Eriksson
Journal:  Eplasty       Date:  2014-10-09

4.  Multi-faceted enhancement of full-thickness skin wound healing by treatment with autologous micro skin tissue columns.

Authors:  Christiane Fuchs; Linh Pham; Jermaine Henderson; Katherine J Stalnaker; R Rox Anderson; Joshua Tam
Journal:  Sci Rep       Date:  2021-01-18       Impact factor: 4.379

5.  Fractional Skin Harvesting: Autologous Skin Grafting without Donor-site Morbidity.

Authors:  Joshua Tam; Ying Wang; William A Farinelli; Joel Jiménez-Lozano; Walfre Franco; Fernanda H Sakamoto; Evelyn J Cheung; Martin Purschke; Apostolos G Doukas; R Rox Anderson
Journal:  Plast Reconstr Surg Glob Open       Date:  2013-10-07

6.  Reconstitution of full-thickness skin by microcolumn grafting.

Authors:  Joshua Tam; Ying Wang; Linh N Vuong; Jeremy M Fisher; William A Farinelli; R Rox Anderson
Journal:  J Tissue Eng Regen Med       Date:  2016-06-14       Impact factor: 3.963

  6 in total

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