[Cigarette smoking and immunity disorder].

Cigarette smoking addiction is one of the cardinal factors the diseases of respiratory system, cardio-vascular system and neoplasms. A part of them is the effect of immunosupression. It includes both morphologic changes (atrophia of lymphoid tissue) and cell functional disorder of the immune system. Cell-mediated response Th1-type, which is responsible for pathogens invasion, is depleted, whereas Th2-type is increased and has its effect on higher frequency of allergic diseases. Susceptibility to neoplasmatic changes is also augmented.